微波辐射下2-苯并咪唑基烯烃的一步法合成  

One-step Synthesis of 2-Benzimidazolyl Alkene under Microwave Irradiation

作　　者：潘文龙[1] 宋继国[1] 余伟杰[1] 陈泳[1] 万一千[1] 宋化灿[1] 

机构地区：[1]中山大学化学与化学工程学院,广东广州510275

出　　处：《中山大学学报（自然科学版）》2006年第6期58-61,66,共5页Acta Scientiarum Naturalium Universitatis Sunyatseni

基　　金：广东省科技攻关资助项目(2003C103006)

摘　　要：以8种肉桂酸衍生物和邻苯二胺为原料，存多策磷酸（PPA）中，采用分段式微波辐射方法合成了8种2-苯并咪唑基烯烃衍生物，并通过^1H NMR、^13C NMR和MS进行了表征。该反应时间为6～10min，比传统的合成方法明显缩短，产率为47％～94％（2-苯丁基苯并咪唑除外），后处理简单，为该类化合物的合成提供了一种新方法。Eight kinds of 2-benzimidazolylalkylene derivatives in polyphosphoric acid （PPA） have been synthesized by multi-power bands microwave irradiation technique, starting from corresponding cinnamic acid compounds and they were characterized by ^1H NMR, ^13C NMR and MS respectively. The reaction time was decreased to 610 minutes which is more shorter than that of traditional method. The yields were from 47% - 94% and the purification of the product was simple. This work could offer a new method for the synthesis of 2-benzimidazolylalkylene derivatives.

关 键 词：微波 2-笨并咪唑基烯烃衍生物 合成 

分 类 号：O626.23[理学—有机化学]