甘露低聚糖对小鼠肠道菌群的调节作用  

Accommodation of mannooligo saccharides on colonies in intestinal tract of rats

作　　者：张力华[1] 黄代勇 王卫华[1] 李开军[1] 盛洪[1] 周小红[1] 

机构地区：[1]华中科技大学同济医学院附属梨园医院老年病科,湖北武汉430077 [2]武汉东方天琪生物工程公司,湖北武汉430015

出　　处：《中国中西医结合消化杂志》2006年第6期380-382,共3页Chinese Journal of Integrated Traditional and Western Medicine on Digestion

基　　金：湖北省卫生厅资助课题(W01530)

摘　　要：[目的]研究甘露低聚糖(MOS)对小鼠肠道菌群的调节作用。[方法]40只小鼠随机分为空白对照组及MOS大、中、小剂量组。于不同剂量的MOS灌胃10 d前后分别采集小鼠粪便,检查肠道内双歧杆菌、乳杆菌、肠杆菌及肠球菌。[结果]MOS中、大剂量组灌胃MOS 10 d前后比较,小鼠肠道内双歧杆菌、乳杆菌数量明显增加(P<0.01),肠杆菌、肠球菌数量无明显变化(P>0.05)。[结论]MOS能有效调节肠道菌群,增殖双歧杆菌及乳杆菌。[Objective]To study the accommodation of mannooligo saccharides on the colonies in rat＇s intestinal tract. [Methods]Forty rats were randomly divided into 4 groups： control group, large-, medium- and low-dose group. Different doses of mannooligo saccharides were given by intragastric administration. Routine excrement examination of bacterial culture, such as Bacillus bifidus, Bacillus acidi lactici, enteric bacilli and enterococci, were made before and after ten days of administration. [Results] The quantity of Bacillus bifidus and Bacillus acidi lactici increased obviously （P〈0. 01）, while the quantity of enteric bacilli and enterococci had no apparent change （P〈0.05）. [Conclusion]The mannooligo saccharides can effectively accommodate the quantity of intestinal tract colonies by improving Bacillus bifidus , Bacillus acidi lactici.

关 键 词：甘露低聚糖 肠道菌群 

分 类 号：Q539[生物学—生物化学] R378.2[医药卫生—病原生物学]