野玫瑰根多糖对家兔急性血清病型肾炎肿瘤坏死因子水平的影响  

The effect of rosa davurica pall root (RDPR)on TNF level in A ESSR rsbbits

作　　者：孔心涓 白丰沛[1] 孔心冰 金玉芝 

机构地区：[1]佳木斯医学院免疫教研室,154003 [2]集贤县医院药剂科 [3]佳木斯医学院病理教研室

出　　处：《佳木斯医学院学报》1996年第4期15-16,共2页

摘　　要：本文采用肿瘤坏死因子(TNF)单克隆抗体的ELISA法检测了家兔急性血清病肾炎(AESSR)血清肿瘤坏死因子水平,并用中药野玫瑰多糖进行治疗。发现模型对照组肿瘤坏死因子水平明显升高。和治疗组相比有显著性差异(P<0.05),提示肿瘤坏死因子在急性肾炎的发病机理中有一定的意义,而野玫瑰根多糖通过调节其分泌而对急性肾炎有一定的治疗作用。The serum TNF level was measured in AESSR rabbits by McAb ELISAmethod. Rosa davuri- ca pall root(RDPR)was used to the AESSR. The result showed that TNF level was increased in model groups, there was a significant difference between model and RDPR groups (p<0.05), Sug- gesting that TNF level was an important factor in AESSR and that RDPR had some effects on the tratement of AESSR by mediating TNF serection.

关 键 词：家兔 急性 血清病肾炎 肿瘤坏死因子 

分 类 号：R692.3[医药卫生—泌尿科学]