原发性痛风性肾病危险因素Logistic回归分析  

The Logistic regression about the risk factors of urate nephropathy in 82 cases of patients with gout.

作　　者：黄海东 李烨 

机构地区：[1]武汉市普仁医院风湿科,湖北武汉430081

出　　处：《中国冶金工业医学杂志》2006年第6期644-646,共3页Chinese Medical Journal of Metallurgical industry

摘　　要：目的:探讨痛风性肾病的危险因素,为痛风性肾病提供二级预防依据。方法:应用Logistic回归分析模型分析我院2003-2005年收治的82例男性痛风住院患者中的48例痛风性肾病的相关危险因素。结果:高血压史、高胆固醇血症和高密度脂蛋白降低与痛风性肾病呈正相关;而饮酒史及早期发现高脂血症病史与痛风性肾病呈负相关;年龄、职业、吸烟及住院期间尿pH值与痛风性肾病无显著相关。结论:长期积极地控制高血压、高胆固醇血症及提高高密度脂蛋白水平是进行痛风性肾病二级预防的有效措施,但痛风性肾病与饮酒的关系需进一步探讨。Objective：To explore the risk factors on urate nephropathy. Methods：We collect 82 cases of patient with gout,among them,there are 48 cases of urate nephropathy atient. And to analyze the risk factors of these 48 cases of urate nephropathy with Logistic Regression. Results; Hypertension, High cholesterol sickness and Low high density fat proteinemia are positive correlation with urate nephropathy, While drinking and early found history of hyperlemia are negative correlation with urate ncphropathy. Age, profession, smoking and urine pH have no correlation with urate nephropathy. Conclusions：Treatmant actively with hypertation, Hematuria acid concentration, High cholesterol sickness and Low high density fat proteinemia are effective secondary prevention measurements, but the correlation between drinking and urate nephropathy need more investigation.

关 键 词：痛风性肾病 危险因素 回归分析 

分 类 号：R589.7[医药卫生—内分泌]