针药预防胆固醇性胆囊结石的实验研究  

Experimental Research on Prevention of Cholesterol Gallstone with Fangshi Capsule Combining with Auricular-plaster Therapy

作　　者：李健[1] 杨卓欣[1] 张永斌[2] 黄明河[1] 张竞超[1] 郭绍举[1] 

机构地区：[1]广州中医药大学附属深圳市中医院,广东深圳518033 [2]广州中医药大学动物实验中心,广东深圳518033

出　　处：《中国中医药信息杂志》2006年第12期35-36,共2页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：广东省中医药管理局科研课题(401052);深圳市医学重点专科及科技计划(200204236)

摘　　要：目的观察耳压及防石胶囊预防胆固醇性胆囊结石的作用。方法将75只豚鼠随机分成5组。空白组喂普通饲料,模型组喂胆固醇结石诱石饲料,熊去氧胆酸(UDCA)组喂胆固醇结石诱石饲料加UDCA,防石组喂胆固醇结石诱石饲料加防石胶囊,耳压组喂胆固醇结石诱石饲料并每天耳穴按压。结果实验2个月后发现:胆囊结石发生率及胆汁中钙离子浓度依次为:模型组>3个治疗组(耳压组、UDCA组、防石组)>空白组,统计学上差异有显著性意义。结论耳压及防石胶囊能预防胆囊胆固醇性结石的形成,其机制可能和它们能分别降低胆汁中钙离子浓度有关。Objective To observe the effect of Fangshi capsule with Auricular-plaster therapy on experimental gallstone guinea pigs. Method Seventy five female guinea pigs were randomly divided into five groups blank group, model group, UDCA group, Fangshi group and Auricular piaster group. All animals were fed with corresponding feeds for two months. Results There were significant difference of gallstone rate and Ca^2＋ of bile of five groups, model group〉therapy group （Auricular-plaster group, UDCA group, Fangshi group） 〉blank group. Conclusion Fangshi capsule combining with Auricular-plaster therapy could prevent the formation of cholesterol gallstone possibly by reducing the calciurn ion concentration in the bile.

关 键 词：胆固醇性胆结石 耳压 防石胶囊 豚鼠 

分 类 号：R285.5[医药卫生—中药学]