强心复脉颗粒对急性血瘀模型大鼠血液流变学的影响  

Effect of Qiangxin Fumai Granule on Hemorheology of Rat Model with Acute Blood Stasis

作　　者：刘如秀[1] 房玉涛[1] 万素君[1] 刘金凤[1] 刘俊辉[2] 刘志明[1] 

机构地区：[1]中国中医科学院广安门医院,北京100053 [2]中国中医科学院中医药信息研究所,北京100700

出　　处：《中国中医药信息杂志》2006年第12期42-43,共2页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：国家中医药管理局资助课题(02-03LP53)

摘　　要：目的研究强心复脉颗粒活血化瘀的作用。方法采用皮下注射肾上腺素加冰水冷浴方法复制大鼠血瘀模型。强心复脉颗粒灌胃后腹主动脉取血,进行血液流变学参数的测定。结果强心复脉组与对照组相比,低切率下全血粘度、红细胞聚集指数及纤维蛋白原含量均明显降低(P<0.05)。结论强心复脉颗粒能改善急性“血瘀”证大鼠血液流变学的指标,降低低切率下的全血粘度,抑制红细胞聚集,降低纤维蛋白原含量,且较复方丹参片好。Objective To study the effect of promoting blood circulation to remove blood stasis by Qiangxin Fumai Granule （QXFMG）. Method The rat model with blood stasis was induced by the hyodermic injection of adrenaline and ice water-bathing. The blood sample was collected by the puncture of the abdomen aorta and the effect of QXFMG on hemorheological parameters was observed. Result Comparing with the control groups, the QXFMG groups can depress the whole blood viscosity under low shear rate, the erythrocytic clustering index and the content of fibrinogen obviously. Conclusion QXFMG can improve the hemorheology level of rat with acute blood stasis by depressing the whole blood viscosity under low shear rate, restraining the clustering of erythrocyte and depressing the content of fibrinogen, which is prior to the Compound Danshen piece.

关 键 词：强心复脉颗粒 血液流变学 大鼠 

分 类 号：R285.5[医药卫生—中药学]