乳母乳汁生长因子变化  

Changes of Growth Factors in Human Breast Milk

作　　者：孙晓勉[1] 王维清[2] 刘黎明[3] 贾梅[4] Kevin Acheson 郑崇勋[1] 

机构地区：[1]西安交通大学生命与技术科学学院生物医学工程研究所,西安720021 [2]西安交通大学医学院儿少卫生教研室 [3]西安交通大学医学院第一附属医院妇幼保健中心 [4]雀巢中国公司医学部 [5]雀巢瑞士国际研究中心

出　　处：《中国临床营养杂志》2006年第6期382-384,共3页Chinese Journal of Clinical Nutrition

基　　金：瑞士儿童营养国际合作项目(99001)

摘　　要：目的通过对55例农村乳母乳汁中表皮生长因子、胰岛素样生长因子Ⅰ和转化生长因子β1等生长因子的测定,探讨其在婴幼儿期乳母乳汁中的含量及分布情况。方法随机整群选取陕西省澄城县5个村55名身体健康的农村乳母,测定其乳汁中生长因子表皮生长因子、胰岛素样生长因子Ⅰ和转化生长因子β1的浓度。结果1～17个月乳母乳汁中表皮生长因子、胰岛素样生长因子Ⅰ和转化生长因子β1的浓度变化不大(P>0.05)。结论母乳中表皮生长因子、胰岛素样生长因子Ⅰ和转化生长因子β1可促进婴幼儿生长发育,建议在合理添加辅助食品的情况下适当延长母乳喂养至1岁半。To study the effects of growth factors in human breast milk on the growth and development of infants by detection of the growth factors, such as epidemal growth factor （EGF） , insulin-like growth factor- I （IGF- I ） and transforming growth factor-β1 （TGF-β1 ） in breast milk of 55 breast-feeding women. Methods Using random cluster sampling method, we randomly selected 55 healthy rural breast-feeding women in 5 villages of Cheng Cheng County, Shaan Xi Province and detected the concentrations of various growth factors such as EGF, IGF- I , and TGF-β1 in their breast milk. Results In negard of concentrations of IGF-1, EGF, and TGF-β1, there was little change in breast milk during the first seventeen months （ P 〉 0, 05 ）. Conclusion Detection of such growth factors as EGF, IGF-1, and TGF-[31 in breast milk was helpful to further study their effects on the growth and development of infants.

关 键 词：母乳 表皮生长因子 胰岛素样生长因子I 转化生长因子Β1 

分 类 号：R174[医药卫生—妇幼卫生保健]