心肌康颗粒对麻醉开胸犬血流动力学的影响  

Effect of Xinjikang granule on hemodynamics in anesthetized chest-open dogs

作　　者：崔新颖[1] 刘惠民[2] 

机构地区：[1]北华大学药学院,吉林132013 [2]北华大学附属医院

出　　处：《中国地方病防治》2006年第6期338-340,共3页Chinese Journal of Control of Endemic Diseases

基　　金：吉林省科技厅资助项目(942905)

摘　　要：目的本实验观察心肌康颗粒对正常麻醉开胸犬血流动力学的影响。方法用电磁流量计分别测量冠脉血流量及心输出量,用载波放大器测定左室内压。结果心肌康颗粒可增加心输出量(CO)、冠脉血流量,降低左室舒张末期压(LVEDP)、总外周阻力及冠脉阻力。结论心肌康颗粒可明显降低心肌耗氧量及冠脉阻力,对心脏血流动力学有明显的改善作用。Objective To study the effects Xinjikang granule on hemodynamics in anesthetized chest - open dogs. Methods The coronary blood flow and cardiac output were measured by electromagnetic flow meter. The internal pressure of left ventricle was determined by carrier amplifier. Results Xinjikang granule could increase the cardiac output and coronary blood flow and reduce the LVEDP, the total peripheral resistance, the coronary blood resistance. Conclusions Xinjikang granule can significandy reduce the myocardial oxygen consumption and coronary blood resistance and can ameliorate the hemodynamics.

关 键 词：心肌康颗粒 麻醉开胸犬 血流动力学 

分 类 号：R285[医药卫生—中药学]