壮尔颗粒治疗小儿反复呼吸道感染50例临床观察  

Clinical Observation on Zhuang'er Granules in Treatment of 50 Children of Recurrent Respiratory Tract Infection

作　　者：宋铁玎[1] 李红[2] 王雪峰[1] 龙旭浩[1] 张君[1] 

机构地区：[1]辽宁中医药大学附属医院儿科 [2]辽宁中医药大学

出　　处：《中医杂志》2006年第12期917-919,共3页Journal of Traditional Chinese Medicine

基　　金：沈阳市科技委员会重点项目(1032041-1-04)

摘　　要：目的:观察壮尔颗粒治疗小儿气阴两虚型反复呼吸道感染(RRTI)的临床疗效。方法:将86例气阴两虚型RRTI患儿随机分为壮尔颗粒治疗组和卡慢舒口服液对照组,均治疗1个月,随访6个月,观察两组治疗前后的发病次数、主要症状,检测T细胞亚群、免疫球蛋白及补体C3。结果:两组总有效率分别为90.0%和80.6%,差异有显著性意义(P<0.05);治疗前后两组症状改善,差异有显著性意义(P<0.05);治疗后两组CD3、CD4、CD4/CD8及IgA、IgG、补体C3均明显升高,组内比较差异有显著性意义(P<0.05或P<0.01)。结论:壮尔颗粒是治疗小儿气阴两虚型RRTI的有效方剂。To observe the therapeutic effect of Zhuang＇er Granules on infantile recurrent respiratory tract infection with syndrome of qi and Yin deficiency. Methods ： Eighty-six children of recurrent respiratory tract infection with syndrome of both qi and Yin deficiency were randomly divided into two groups,a treatment group treated by Zhuang＇er Granules and a control group by Kamanshu oral liquor. They were treated for one month and then followed up for 6 months. Recurrent times, clinical main symptoms, T cell subpopulation,immunoglobulins and complement-3 （C3） were determined before and after treatment. Results：The total effective rate in the treatment group （90. 0%） was significantly higher than 80. 6 % in the control group （P〈0. 05）. After treatment, improvement of symptoms in the treatment group was better than in the control group （P〈0. 05）. CD4,CD8,CD4/ CD8, IgA, IgG and C3 significantly increased in both groups, with significant differences as compared with those before treatment （P〈0.05 or P〈0.01）. Conclusion ：Zhuang＇er Granules is an effective prescription for treatment of infantile recurrent respiratory tract infection with syndrome of both qi and Yin deficiency.

关 键 词：呼吸道感染工中医药疗法 气阴两虚/中医药疗法 @壮尔颗粒 

分 类 号：R272[医药卫生—中医儿科学]