经皮穿刺二尖瓣球囊成形术的再狭窄及远期疗效  

Restenosis and long-term outcome after percutaneous balloon mitral valvuloplasty

作　　者：苗来生[1] 戴汝平 黄连军 荆宝莲 

机构地区：[1]大同医专内科教研室 [2]国医学科学院阜外心血管病医院

出　　处：《大同医专学报》1996年第2期9-14,共6页

基　　金：美国中华医学基金会(CMB)奖学金

摘　　要：1986～1995年9月成功地进行了PBMV治疗800余例,对其中随访资料完整的160例进行了回顾性研究,着重研究了再狭窄率,远期疗效及影响因素。其中男55例,女105例,平均年龄38.9±8.9岁(15～68岁)。术后定期复查,全部资料经计算机统计处理,对影响远期疗效的因素,用COX风险模型作了分析。PBMV术后平均随访36±15个月(12～81个月),127例心功能持续改善。超声心动图测得的二尖瓣口面积,术前、术后及随访分别为1.15±0.2,2.15±0.4和1.92±0.4cm^2。26例(17％)发生了再狭窄,17例症状复发,9例无症状。研究结果显示,PBMV术后可保持较好的远期疗效,超声心动图记分,心功能,心律(有无房颤)This study reports the clinical follow -up of 160 patients who underwent percutaneous balloon mitral valvuloplasty(PBMV) ,in order to identify the long-term outcome, the incidence of restenosis and the factors of the determing restenosis.Material and methods . PBMV was performed successfully in 160 of patients with mitral stenosis. It resulted in an increase in the mean (±SD) mitral - valve area from 1. 15 ±0. 2 to2. 14±0. 4cm2. This series included 105 females and 55males. The mean age was 38. 9±8. 9 years (15-68years). They were followed-up after the precedure. The data was analyzed with SAS software. Results:Follow-up of 12-81 months(median 36±15 month)showed a symptomatic improvement rate of79%(127 patients). Mitral-valve area was 1. 92±0. 4cm2 ,Restenosis was demonstrated in 26 patients (17 %). According to multivariate COX-proportional -hazardsanalysis. The independent predictors oflonger event-free survival were a mitral-valve echocar-diographic score,rhythm, New Yord Heart Association class and atrial pressure. PBMV as atreatment for selected patients with mitral stenosis has good long-term results.

关 键 词：二尖瓣 球囊成形术 再狭窄 心脏外科手术 疗效 

分 类 号：R654.2[医药卫生—外科学]