脂蛋白a与不稳定心绞痛关系研究  被引量:1

The Correlation of lipoprotein (a) with unstable angina pectoris

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作  者:张建[1] 王君[1] 

机构地区:[1]江苏省镇江市第一人民医院心内科,江苏镇江212000

出  处:《海南医学》2007年第1期17-18,共2页Hainan Medical Journal

摘  要:目的探讨血浆脂蛋白(a)[LP(a)]水平与不稳定心绞痛患者冠状动脉病变程度及范围的关系,以明确LP(a)在冠心病发生、发展及急性冠状动脉事件中的作用。方法测定211例冠脉造影患者的LP(a)、血浆总胆固醇(TC)、甘油三酯(TG),高密度脂蛋白,低密度脂蛋白,载脂蛋白A的血浆浓度。结果(1)不稳定性心绞痛患者血浆LP(a)水平高于正常对照组(P<0.05);(2)血浆LP(a)水平与其它血脂没有相关性。(3)不稳定心绞痛患者体内脂蛋白水平与冠状动脉病变范围及程度无明显相关性。结论LP(a)在不稳定心绞痛发病中具有一定作用,对冠心病的诊断判断具有一定意义。Objective To explore the correlation of LP (a) to the extent, severity and stability of coronary artery disease and its relation to unstable angina. Methods In 211 patients undergoing coronary angiography, LP (a) and plasma lipids were measured with usual procedures. Results (1) There was a positive association between LP(a) and unstable angina (P〈0.05). (2) There was no relation between Lp(a) and plasma lipids. (3)we had not yet found any relationship between LP (a) and the extent and severity of coronary artery disease, Conclusions Elevated L P (a) predisposes to the destabilization of coronary artery disease, Lp (a) is an independent factor to detect the patient incline to coronary disease.

关 键 词:脂蛋白(a) 冠状动脉造影术 不稳定心绞痛 

分 类 号:R541.4[医药卫生—心血管疾病]

 

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