同种异体动脉在平时四肢大血管火器伤修复中的应用  

Clinical application of homologous transplantation of arteries in firearm injuries of great vessels of extremities

作　　者：吴文[1] 尹庆水[1] 章莹[1] 王炜[1] 文治强[1] 

机构地区：[1]广州军区广州总医院骨科,广州510010

出　　处：《解放军医学杂志》2006年第12期1192-1193,共2页Medical Journal of Chinese People's Liberation Army

摘　　要：目的探讨平时四肢大血管火器伤中血管损伤的修复方法。方法2002年5月～2005年9月，应用15条经深低温保存的同种异体动脉移植修复肱动脉损伤5例、腋动脉损伤1例，胴动脉损伤1例、股动脉缺损7例（14例患者），移植血管平均长9．5cm。术后按显微外科常规观察治疗效果。结果14例术后均无早期排异反应，伤口经Ⅱ期处理后全部愈合，愈合后2～3周经超声多普勒检测，血管通畅率为100％。随访4～12个月，肢体功能恢复良好，未见迟发排异反应。结论经深低温处理的同种异体动脉可作为临床修复平时四肢大血管火器伤较为理想的生物性材料。Objective To study the repair of great vessels injured by firearm in extremities. Methods From May 2002 to Sep. 2005, 15 cryopreserved homologous arteries were transplanted to repair the defects of great vessels of extremities in 14 patients, including 5 cases of defect of brachial arteries, 1 case of defect of axillary artery, 1 case of popliteal artery damage and 7 cases of defect of femoral arteries. The average length of homologous arterial transplants was 9.5 cm. After operation, all the 14 patients were monitored and treated according to principles of microsurgery. Result No early reject reaction was found in all the 14 cases, and all the wounds healed after Ⅱ stage treatment. With Doppler ultrasonic examination 2-3 weeks after healing, it was proved that 100% of the vessels were patent. In 4 to 8 month follow up, the function of the extremities recovered well, and no delayed reject reaction was observed. Conclusion The vessels after cryopreservation is a suitable biomaterial in homologous transplantation for repairing the defect of great vessels of the extremities as a result of firearm injury.

关 键 词：移植 同种 动脉 低温保存 火器伤 

分 类 号：R826.51[医药卫生—临床医学] R622.4