经皮层选择性海马杏仁核切除术治疗颞叶癫痫  

Treatment of temporal lobe epilepsy using transcorticai selective mygdalohippocampectomy

作　　者：许尚臣[1] 栾立明[1] 庞琦[1] 翟国德[1] 葛明旭[1] 孔大伟[1] 

机构地区：[1]山东大学山东省立医院神经外科,济南250021

出　　处：《中华神经外科杂志》2006年第12期732-734,共3页Chinese Journal of Neurosurgery

基　　金：山东省自然科学基金(基金编号:05200140)

摘　　要：目的观察经皮层入路选择性海马杏仁核切除术对颞叶癫痫的治疗效果及风险。方法20例单侧海马硬化性顽固性颞叶内侧癫痫患者,采用颞部开颅经颞中回侧脑室入路选择性海马杏仁核切除术治疗,随访至少1年以上,采用Engel分级量表进行针对癫痫发作控制效果的评价。结果Ⅰ级结果15例,Ⅱ级结果3例,Ⅲ级结果2例,无明显持久性并发症,无手术死亡。结论在严格筛选的颞叶内侧癫痫,颢部开颅经颞中回皮层入路选择性切除海马杏仁核术对治疗颞叶癫痫,安全有效。Objective To observe the effectiveness and associated risks of trans-midtemporal transventricle selective amygdalohippocampectomy via keyhole temporal craniotomy in treating mesial temporal lobe epilepsy. Methods 20 patients with intractable mesial temporal lobe epilepsy associated with unilateral hippocampal sclerosis were treated surgically using this surgical procedure and had been followed up more than 1 year. The outcome with respect to seizure control was evaluated according to Engel＇s outcome classification system. Results Class one outcome was obtained in 15 patients, class two outcome in 3 patients, class three outcome in 2 patients. No surgical mortality. No persistent neurological complications occurred. Conclusion In strictly selected patients with mesial temporal lobe epilepsy, this procedure is highly effective and safe.

关 键 词：颞叶癫痫 海马硬化 选择性海马杏仁核切除术 

分 类 号：R651.1[医药卫生—外科学]