支气管肺炎患儿治疗前后血清TNF-α、IGF-Ⅱ、IL-6检测的临床意义  

Clinical Significance of Measurement of Changes of Serum TNF-α,IGF-Ⅱ and IL-6 Levels After Treatment in Pediatric Patients with Bronchopneumonia

作　　者：李红梅[1] 

机构地区：[1]江苏省连云港市第一人民医院儿科,222002

出　　处：《放射免疫学杂志》2006年第6期463-464,共2页Journal of Radioimmanology

摘　　要：目的探讨了血清TNF-α、IGF-Ⅱ、IL-6水平在支气管肺炎患儿治疗前后的变化及意义。方法应用放免法测定36例支气管肺炎患儿治疗前后TNF-α、IGF-Ⅱ、IL-6水平,并与30名正常儿作比较。结果支气管肺炎患儿治疗前均非常显著地高于正常儿组(P<0.01),治疗后2周与正常儿比较无显著差异(P>0.05)。结论检测支气管肺炎患儿血清TNF-α、IGF-Ⅱ、IL-6水平可作为病情预后判断的重要指标。Objective To investigate the significance of changes of serun TNF-α、IGF-Ⅱ and IL-6 levels after treatment in pediatric patients with bronchopneumonia.Methods Serum TNF-α、IGF-Ⅱ and IL-6 levels（with RIA）were determined in 36pediatric patients with bronchopneumonia both before and after treatment and 30 controls. Results Before treatment, the serum TNF-α, IGF- Ⅱ and IL-6 levels in the patients were significantly higher than those in controls （P 〈0.01 ）, after treatment for two weeks, the TNF-α, IGF- Ⅱ and IL-6 levels were about the same （ P 〉 0.05 ） as those in controls. Conclusion Detection of serum TNF-α, IGF- Ⅱ and IL-6 levels is clinically useful in the management of pediatric patients with bronchopneumonia.

关 键 词：支气管肺炎 

分 类 号：R562[医药卫生—呼吸系统]