鲑鱼降钙素配合康复疗法治疗腰椎管狭窄症  

Salmon calcitonin plus rehabilitative therapy for lumbar spinal stenosis

作　　者：成鹏[1] 马诚[2] 王新丽[2] 郎海涛[1] 

机构地区：[1]解放军第二军医大学长海医院康复医学科,上海市200433 [2]克拉玛依市中心医院康复医学科,新疆维吾尔自治区克拉玛依市830001

出　　处：《中国临床康复》2006年第47期32-34,共3页Chinese Journal of Clinical Rehabilitation

摘　　要：目的:观察鲑鱼降钙素配合传统综合康复疗法治疗椎间盘突出所致腰椎管狭窄症的有效性和安全性。方法:①选择2004-01/2005-12在解放军第二军医大学长海医院康复医学科和克拉玛依市中心医院康复医学科门诊就诊的80例腰椎管狭窄症患者,按病例号奇偶数分别编入对照组和观察组,各40例。②对照组给予常规康复治疗,采用卧位骨盆牵引治疗、磁热振治疗、低周波治疗3种方法,共治疗6周。观察组在此基础上给予鲑鱼降钙素注射治疗,使用方法:50IU肌注,1次/d,共14d,继续50IU肌注,隔日1次,共28d,共治疗6周。③治疗后对两组患者疼痛情况、腰部活动范围、跛行状况、下肢反射、日常生活能力进行评定。结果:80例患者均进入结果分析。①视觉模拟量表疼痛评分:观察组低于对照组(0.78±0.76,1.53±1.51),差异有显著性意义(P<0.05)。②腰部活动范围:观察组大于对照组[屈:(2.65±0.48)°,(2.40±0.49)°;伸:(2.80±0.41)°,(2.40±0.55)°],差异有显著性意义(P<0.05)。③跛行评分:观察组高于对照组(4.65±1.35,3.45±0.99),差异有显著性意义(P<0.001)。④下肢反射评分:观察组略低于对照组(膝:0.85±0.36,0.90±0.30;跟踺:0.85±0.36,0.95±0.22),差异无显著性意义(P>0.05)。⑤功能独立性量表评分:观察组略高于对照组(123.73±3.97,122.35±5.04),差异无显著性意义(P>0.05)。⑥治疗过程中有3例出现轻度不良反应,症状轻微未影响治疗正常进行。结论:鲑鱼降钙素具有能迅速减轻腰椎管狭窄症状的作用,尤其是减轻疼痛作用明显,副反应轻微。AIM： To observe the efficacy and safe of salmon calcitonin and traditional comprehensive rehabilitative therapy combination for lumbar spinal stenosis induced by intervertebral disk hernia. METHODS： ①Totally 80 cases of lumbar spinal stenosis. who were treated at Department of Rehabilitation Medicine. Changhal Hospital Affiliated to Second Military Medical University of Chinese PLA and Department of Rehabilitation Medicine. Karamay Central Hospital from January 2004 to December 2005. were divided into observational group and control group with 40 in each group according to odd and even number. ② Routine rehabilitative therapy was given to the control group. Pelvic traction therapy at decumbent position. magnetic force vibration heat therapy. low frequency impulse electrotherapy were applied for 6 weeks. The patients in the observational group received salmon calcitonin by injection. method of using： 50 IU muscle injection. once a day. for 14 days. for 50 IU successively. once another day. for 28 days. totally for 6 weeks. ③Pain condition. range of motion （ROM）. walking distance scale. lower limb reflexes and activity of daily living were assessed in the patients of the two groups after treatment. RESULTS：A total of 80 patients were involved in the result analysis. ① Visual Analogue Scale（VAS）： It was lower in the observational group than the control group （0.78±0.76.1.53±1.51）. and there was significant difference （P〈0.05）. ②ROM： It was larger in the observational group than the control group [flexion： （2.65±0.48）°.（2.40±0.49）° ;extension： （2.80±0.41）. （2.40±0.55）°]. and there was significant difference （P 〈 0.05）. ③walking distance scale： It was higher in the observational group than the control group （4.65± 1.35.3.45±0.99）. and there was significant difference （P 〈 0.001）. ④ lower limb reflexes： It was slightly lower in the observational group than the control group （knee：0.85±0.36.0.90±0.30; tendon：0.85±0.36

关 键 词：腰椎 椎管狭窄 降钙素 康复 

分 类 号：R681.5[医药卫生—骨科学]