含硫的N-甲氧基氨基甲酸甲酯的合成及生物活性  

Synthesis and Fungicidal Activity of Methyl N-Methoxylcarbamates Containing Sulfur

作　　者：李仲英[1] 李世林[1] 刘卫东 兰世林 

机构地区：[1]湖南大学化学化工学院,湖南长沙410082 [2]国家农药创制工程技术研究中心,湖南长沙410007 [3]湖南师范大学化学化工学院,湖南长沙410081

出　　处：《湖南大学学报（自然科学版）》2006年第6期103-105,共3页Journal of Hunan University:Natural Sciences

基　　金：国家'十五'科技攻关项目(2004BA308A22);湖南省杰出青年科学基金资助项目(04JJ1009)

摘　　要：为了寻找高效、低毒的新农药,采用活性结构拼接法合成了7个具有新型结构的N-甲氧基-N-[2-(甲硫基亚甲基-取代苯亚胺-硫亚甲基)苯基]氨基甲酸甲酯化合物.其结构经1H NMR,IR,LC/MS进行了表征.生物活性测定表明:5b,5g在50 mg/L下对稻瘟病(Pyricularia oryzae)的抑菌活性达90%.In order to find new pesticides with higher effectiveness and lower toxicity, seven methyl N- methoxy- N- { 2- [ methylthlomethano （substituted-phenylimino） thlomethylene ] phenyl } -carbamates were synthesized according to the substructure link principle. All compounds were confirmed by IH NMR, IR and LCZMS. The results of preliminary fungicidal tests showed that the inhibitory ratio of 5b and 5g against Pyricularia oryzae were 90.9 % at the concentration of 50 mg/L.

关 键 词：合成 N-甲氧基-N-苯基氨基甲酸酯 亚胺 杀菌活性 

分 类 号：O622.7[理学—有机化学]