肝移植术后中心静脉导管相关性脓毒症临床分析  

Clinical analysis of central venous catheter-related sepsis after liver transplantation

作　　者：陈鹏[1] 李波[1] 严律南[1] 邓小凡[1] 李晋[1] 曾勇[1] 文天夫[1] 赵继春[1] 

机构地区：[1]四川大学华西医院肝移植中心,成都610041

出　　处：《中国感染与化疗杂志》2006年第6期396-398,共3页Chinese Journal of Infection and Chemotherapy

摘　　要：目的分析肝移植术后中心静脉导管相关性脓毒症(CRS)的临床特点,病原菌分布及药敏情况。方法对1999年2月—2005年6月我院实施的260例肝移植患者作回顾性分析。结果肝移植术后 CRS 发生率为9.2%,金葡菌和表皮葡萄球菌是最常见病原体;分离的病原菌耐药性较高。革兰阳性球菌对万古霉素均敏感。结论可疑 CRS 拔除导管后体温不降,又未发现其他感染灶,应根据药敏试验结果选用有效抗菌药。Objective To investigate the clinical characteristics, bacteria spectrum and drug-sensitivity in patients with central venous catheter-related sepsis （CRS） after liver transplantation. Methods A retrospective study was carried out among 260 patients who had received liver transplantation between February 1999 and June 2005. Results The incidence of CRS after liver transplantation was 9.2 %. The most common organisms were Staphylococcus aureus and Staphylococcus epiderrnidis. The isolated pathogens demonstrated high antibiotic resistance. All gram-positive cocci were sensitive to vancomycin. Conclusions Effective antimicrobial agent can be selected according to the results of susceptibility testing for the patients with fever after removal of catheters if they are suspected of CRS after liver transplantation and no other site of infection is identified.

关 键 词：肝移植 中心静脉导管 脓毒性综合征 

分 类 号：R657.3[医药卫生—外科学] R459.7[医药卫生—临床医学]