内皮素系统与卵巢功能  

Endothelin system and ovary function

作　　者：肖秋香[1] 高凤兰[2] 郑月慧[2] 

机构地区：[1]赣南医学院病理教研室,赣州341000 [2]南昌大学医学院生理生殖研究室,南昌330006

出　　处：《生殖医学杂志》2006年第6期417-420,共4页Journal of Reproductive Medicine

基　　金：国家自然科学基金资助(30260035)

摘　　要：内皮素是哺乳动物体内新发现的一类生物活性肽,内皮素及其受体广泛分布于动物体内多种组织和器官,以旁分泌和自分泌方式参与机体各系统的功能调节。卵巢中存有内皮素及其受体,内皮素对卵巢的内分泌功能、卵泡发育、排卵、黄体生成及溶解等各种功能均起着重要的调节作用,并与卵巢疾病的发生有着密切关系。Endothelins（ETs） are a newly identified family of bioactive peptides in the mammals. ETs and their receptors are present in a variety of tissues and organs. They regulate various functions by autocrine and paracrine manners. The presence of ETs and their receptors in ovary contributes to the regulation of endocrine, follicle development, ovulation, corpus luteum formation and luteolysis, and may also play an important role in the development of ovarian diseases. The mechanisms might be in relation to PKA and PKC pathway.

关 键 词：内皮素 内皮素受体 卵巢功能 

分 类 号：R335.5[医药卫生—人体生理学]