小剂量肝素治疗恙虫病并发DIC的临床疗效  

To investigate the clinical effectiveness of using mlcodose of heparin in disseminated intravascular coagulation caused by Tsutsugamushi

作　　者：蔡成才[1] 陈建军[1] 林小峰[1] 

机构地区：[1]肇庆市第一人民医院血液内科,广东省肇庆526021

出　　处：《中国基层医药》2006年第11期1810-1811,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的探讨肝素在恙虫病急性弥散性血管内凝血(DIC)中的临床治疗价值。方法标准进行确诊,把恙虫病并发急性弥散性血管内凝血27例分为肝素组15例和非肝素组12例进行对比治疗分析。结果使用肝素组在终止出血、DIC实验室指标恢复时间、器官功能衰竭发生率、死亡率等方面均有明显改善,两组疗效比较,差异有统计学意义(P<0．05)。结论小剂量肝素有利于终止恙虫病急性弥散性血管内凝血的病理进程、改善器官血流灌注,降低器官功能衰竭发生率、死亡率,缩短治愈时间。Objective To explore the clinical value of using heparin in DIC caused by Tsutsugamushi. Methods 27 cases of Tsutsugamushi with DIC were divided into two groups. The heparin treatment group（ n = 15） and non-heparin treatment group（ n = 12）. The two groups were compared and analyzed. All the cases were diagnosed definitely depended on the ＂Tsutsugamushi-Disease-Diagnosis Standard＂. Results The group which use hepafin improved in rectifying shock, terminating heorrhage, restoring the time of lab index of DIC,rating of MOF and death. Compared with the control group, the difference had statistical significance（ P 〈 0.05 ）. Conclusion Using micodose of heparin is benefical to terminate the progress of DIC caused by Tsutsugamushi, decrease the rate of MOF and death,shorten the time of rescuing and improve hemoperfusion of organ.

关 键 词：肝素 急性弥散性血管内凝血 恙虫病 

分 类 号：R513.2[医药卫生—内科学]