邻二氮杂菲银/蒙脱石抗菌复合物的制备及表征  

PREPARATION AND CHARACTERIZATION OF ANTIBACTERIAL COMPOUND OF SILVER CHELATE OF 1,10-PHENANTHROLINE /MONTMORILLONITE

作　　者：杨丹[1] 袁鹏[1] 朱建喜[1] 何宏平[1] 

机构地区：[1]中国科学院广州地球化学研究所

出　　处：《矿物岩石》2006年第4期14-18,共5页Mineralogy and Petrology

基　　金：广东省自然科学基金项目(批准号:023203;04002140);广东省科技攻关项目(批准号:013109)

摘　　要：以X射线衍射(XRD)、傅立叶变换红外光谱(FT IR)、激光拉曼光谱(R am an)等手段对用微波辐射法制备邻二氮杂菲银/蒙脱石抗菌复合物抗菌及其热处理产物进行表征,结果显示:邻二氮杂菲与银离子所形成的络离子([A g(phen)2]+)通过离子交换作用进入蒙脱石的层间形成有序插层结构,其d(001)值随热处理温度的上升呈规律性变化,复合物的热稳定性可达300℃。复合物中银离子的溶出量受热处理温度的控制。抗菌性能测试表明复合物及其热处理产物对大肠杆菌都具有良好的抗菌活性。微波辐射法较传统制备方式更为简便、快速。An antibacterial compound of silver chelate of 1,10-phenanthroline/Montmorillonite was synthesized under microwave. The sample and calcined products at different temperature were studied by means of XRD,IR and Raman. The result of X ray diffraction shows that the d001 value of antibacterial compound is 1.85 nm,larger than that of Na-montmorillonite （1.26 nm）, indicating that the silver chelate has been intercalated into the interlayer of montmorillonite. In the corresponding infrared spectrum,the broad line at 1 380 cm^-1,due to the NO3 group in the [Ag（phen）2]^＋NO3 compound,is absent,which indicates that the composite is not a mixture of the montmorillonite and [Ag（phen）2]^＋ NO3^-,but rather of an interlayer complex of the mineral with [Ag（phen）2]^＋ cations. The d001 value distance of the intercalation compounds varied regularity with treatment temperature. According to XRD,IR analysis it is showed that the antibacterial compound was stable up to 300℃, Heating treatment can control the leaching amount of Ag^＋. The resultant antibacterial compounds exhibit good antibacterial activity to E. coli, The results show that the treatment by microwave is superior to the traditional method not only in predigest ing process,but also in shortening the reaction time apparently.

关 键 词：蒙脱石 邻二氮杂菲 抗菌性能 微波辐射 

分 类 号：R979.7[医药卫生—药品]