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作 者:高珊[1] 童英[1] 熊晓燕[1] 张懿[1] 吴少平[1]
机构地区:[1]北京市疾病预防控制中心卫生毒理所,北京100013
出 处:《实验动物科学与管理》2006年第4期4-6,共3页Laboratory Animal Science & Administration
摘 要:目的初步研究玛咖和西洋参对缓解体力疲劳的作用。方法用四批动物,每批70只昆明种小鼠,按体重分成7组,分别给予去离子水,0.040、.4和1.2g/kg玛咖;0.04、0.4和1.2g/kg西洋参,连续灌胃30d后,分别测定四批小鼠负重游泳时间及运动后即刻的血清尿素、肝糖原的含量;运动前、运动后即刻及运动后休息20min的血乳酸含量。结果0.4g/kg和1.2g/kg玛咖可明显延长小鼠负重游泳时间(与阴性组比较P<0.05和P<0.01),0.04和0.4g/kg西洋参能明显延长小鼠负重游泳时间(与阴性组比较P<0.01和P<0.05);3剂量组的玛咖对小鼠血清尿素无明显影响(与阴性组比较P>0.05),1.2g/kg西洋参可显著降低小鼠运动后的血清尿素水平(与阴性组比较P<0.05);3个剂量的玛咖与西洋参均可增加小鼠的肝糖原含量;0.4和1.2g/kg玛咖可降低运动前后血乳酸变化值(与阴性对照组比较P<0.01),各剂量的西洋参对小鼠运动前后血乳酸变化值无明显影响。结论玛咖和西洋参都具有缓解体力疲劳的功能,但两者对小鼠血乳酸和尿素氮的影响不同。Objective To study the effects of maca and american ginseng on relieving physical fatigue. Methods 4 experiments were carried out, in each of which 70 mice were used and they were divided into 7 groups: deionized water, 0.04, 0.4, 1.2g/kg of maca, 0.04, 0.4, 1.2g/kg of american ginseng, administrated to each group for 30 days, respectively. The four tests were used to determine swimming time with weight loading; serum urea instant after exercise; hepatic glycogen; and blood lactose before or instant after or 20 minutes after exercise. Results Compared with the control, 0.4, 1.2g/kg of maca could extend swimming time with weight loading in mice (P 〈 0.05, P 〈 0. 01 ), 0.4, 1.2g/kg of american ginseng could extend swimming time with weight loading (P 〈 0.05, P 〈 0.01 ); maca bad noeffects on serum urea ( P 〉 0.05), 1.2g/kg of american ginseng could reduce serum urea after exercise ( P 〈 0. 05) ; maca and american ginseng could increase hepatic glycogen; 0.4, 1.2g/kg of maca could decrease the fluctuation of blood lactose before and after exercise ( P 〈 0.01 ), american ginseng had no effects on it. Condusion, Both maca and american ginseng can relieve physical fatigue, but they have different effects on blood lactose and serum urea in mice.
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