云芝多糖对小鼠心、肝、脾、肾和红细胞抗氧化能力的影响  

Effect of PSK on antioxidation capacity of mice in vivo

作　　者：娄宁[1] 周玫[1] 陈瑗[1] 

机构地区：[1]第一军医大学自由基医学研究室

出　　处：《中国药理学通报》1996年第5期425-426,共2页Chinese Pharmacological Bulletin

基　　金：国家自然科学基金

摘　　要：通过测定小鼠心、肝、脾、肾组织和红细胞脂质过氧化物含量和硒谷胱甘肽过氧化物酶活性，观察了云芝多糖对机体各组织及红细胞抗氧化能力的影响。结果表明，云芝多糖能提高机体各组织的硒谷胱甘肽过氧化物酶活性及降低脂质过氧化物含量，提示云芝多糖能有效地提高机体抗氧化能力，为防止或减轻脂质过氧化损伤提供了实验依据。The effect of PSK on antioxidation capacity of mice in vivo was observed,by measuring the lipoperoxide(LPO)content and selenium glutathione peroxidase(SeGSHPx)activity.The results demonstrated that PSK could elevated the SeGSHPx activity and decrease the LPO content in vivo efficiently,indicating that PSK could increase the antioxidation capacity in vivo significantly.Experimental data were provided in the assay for preventing the lipoperoxidative damage by PSK.

关 键 词：云芝多糖 过氧化脂质 硒 谷胱甘肽 过氧化物酶 

分 类 号：R285.5[医药卫生—中药学] R282.710.5[医药卫生—中医学]