咪唑安定复合瑞芬太尼在人流术中的应用  

The Clinical Effect of Combination of Midazolam and Remifentanil in Operation of Induced Abortion

作　　者：李鸿志 董文启[2] 

机构地区：[1]江苏省兴化市第二人民医院,225700 [2]江苏省兴化市中医院

出　　处：《医学理论与实践》2006年第12期1398-1399,共2页The Journal of Medical Theory and Practice

摘　　要：目的:评价咪唑安定复合瑞芬太尼在门诊人流术中运用的可行性与安全性。方法:选择自愿作无痛人流术患者60例,随机分为3组,即瑞芬太尼组(R组)、咪唑安定复合瑞芬太尼组(RM组)及对照组。术前2min RM组静注咪唑安定0.04mg/kg,其余两组予相应剂量的生理盐水;术前1min R组及RM组静注瑞芬太尼0.1μg/kg,对照组静注相应剂量的生理盐水。结果:术中血压、血氧、心率,R组、RM组与对照组比较存在显著性差异(P<0.05);R组、RM组术前、术中比较存在显著性差异(P<0.05);焦虑发生率RM组与其他两组存在显著性差异(P<0.05);术后各项指标无显著性差异(P>0.05)。结论:咪唑安定复合瑞芬太尼运用于无痛人流术中是安全可行的。Objective： To evaluate the feasibility and security of midazolam and remifentanil intravenous anesthesia administration for induced abortion in out-patients. Methods： 60 patients who were voluntary to accept painless induced abortion were randomly divided into group R（remifentanil group）, group RM（midazolam and remifentanil group）, and control group. Group RM received midazolam 0. 04mg/kg 2min before operation, the others got the same dose of NS; Group R and group RM received remifentanil 0.1μg/kg lmin before operation, equivalent NS was used in control group. Results： Differences of BP, sPO2 and HR during operation between Group R, Group RM and control group were statistically significant respectively（P〈0. 05）, and all these data observed in Group R, Group RM showed marked differences respectively between preoperation and operation stage（P〈0. 05）. Differences of anxiety occurrence rate between Group RM and the others were remarkable respectively（P〈 0. 05）, all parameters gained after operation in each group were not statistically significant（P〉0. 05）. Conclusion： Midazolam and remifentanil are safe and feasible for painless induced abortion.

关 键 词：咪唑安定 人流 

分 类 号：R714.21[医药卫生—妇产科学]