固-液相转移催化法合成N-芳酰基-N′-芳基硫脲衍生物及其生物活性  

Synthesis and biological activity of N-aroyl-N′-arylthiourea derivatives under the condition of solid-liquid phase transfer catalysis

作　　者：顾生玖[1] 朱开梅[1] 

机构地区：[1]桂林医学院药学院,广西桂林541004

出　　处：《化学研究与应用》2006年第12期1443-1445,共3页Chemical Research and Application

基　　金：广西科技攻关(科技攻关0428008-4J)项目资助;桂林市科技攻关(科技攻关20050105.3)项目资助;广西自然科学基金(桂科自0640190)项目资助

摘　　要：Aroyl isothiocyanate is synthesized by the reaction of aroyl chloride with ammoniurrthiocyanate under the condition of solid1iquid phase transfer catalysis using PEG-400 as the catalyst.The tater needs not to be isolated and is reacted with aromatic amine immediately to give N-aroy 1-N′-aryl thiourea derivatives in high yield.The promoting effects of the title compounds on wheat growth are tested preliminily.Aroyl isothiocyanate is synthesized by the reaction of aroyl chloride with ammoniurrthiocyanate under the condition of solid-liquid phase transfer catalysis using PEG-400 as the catalyst. The tater needs not to be isolated and is reacted with aromatic amine immediately to give N-aroy 1-N＇-aryl thiourea derivatives in high yield. The promoting effects of the title compounds on wheat growth are tested preliminiiy.

关 键 词：N-芳酰基-N-芳基硫脲衍生物 相转移催化 合成 生物活性 

分 类 号：O621.36[理学—有机化学]