水杨酸、对甲氧基苯甲酸和甲硝唑的拉曼光谱  

Raman Spectra of Salicylic Acid,p-Methoxybenzoic Acid and Metronidazole

作　　者：许莉莉[1] 丁库克[1] 郭学谦[1] 王春燕[1] 黄菊英[1] 

机构地区：[1]首都医科大学生物医学工程学院物理教研室

出　　处：《首都医科大学学报》2006年第6期785-787,共3页Journal of Capital Medical University

摘　　要：目的研究水杨酸、对甲氧基苯甲酸和甲硝唑等化合物拉曼光谱的波长选择性。方法分别采用近红外、可见和紫外区3种波长的激光激发获得不同的拉曼光谱,受照样品包括水杨酸、对甲氧基苯甲酸以及临床常用药物甲硝唑。结果水杨酸、对甲氧基苯甲酸的水溶液在可见和近红外激发下无法获得任何拉曼信息,但在紫外激发下可获得信息丰富的拉曼光谱,且与其固体拉曼谱对应良好。而甲硝唑在紫外激发下没有明显的拉曼峰但在近红外和可见光激发下能获得一致的拉曼信息。结论水杨酸、对甲氧基苯甲酸水溶液的拉曼光谱证明了紫外激发的优越性,甲硝唑的拉曼光谱提示样品对激发波长的选择性。Objective To investigate selectivity to excitation wavelength of Raman spectra for several compounds. Methods We obtained the different Raman spectra of some samples with different excitation, mainly including salicylic acid （ SA ）, p-methoxybenzoic acid （p-MBA） and metronidazole. Results The Raman spectra of SA and p-MBA in aqueous solution were correspondent to their solid counterpart at ultraviolet excitation, which could not be observed with visible or near infrared excitation. The high-quality Raman spectra of metronidazole were obtained with visible and near infrared light while there was not any Raman band with ultraviolet. Conclusion The spectra of SA and p-MBA demonstrate the advantages of ultraviolet excitation, but on the other hand the spectra of metronidazole indicate the selectivity of excitation wavelength.

关 键 词：拉曼光谱 水杨酸 对甲氧基苯甲酸 甲硝唑 

分 类 号：O434.13[机械工程—光学工程]