Preparation of High Selective Molecularly Imprinted Polymers for (S)-4-Phenyl-2-oxazolidinone  

作　　者：Yong LUO Lan LIU Li Hong LI Qin Ying DENG 

机构地区：[1]School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou 510275

出　　处：《Chinese Chemical Letters》2006年第12期1551-1554,共4页中国化学快报（英文版）

基　　金：financed by the National Natural Science Foundation of China(No.20202015).

摘　　要：（S）-4-Phenyl-2-oxazolidinone imprinted polymers were prepared by using methacrylic acid （MAA） as the functional monomer, and divinylbenzene （DVB） as crosslinker. The factors, which influence the selectivity of the polymers were explored. Effective separation was observed for racemic 4-phenyl-2-oxazolidinone in mobile phase of acetonitrile. The investigation of mobile phase suggested that the hydrogen bonds between template and functional monomer was a primary factor in chiral recognition, while the preparation of polymers implied that the л-л stacking interaction between template and crosslinker played a role in imprinting procedure.（S）-4-Phenyl-2-oxazolidinone imprinted polymers were prepared by using methacrylic acid （MAA） as the functional monomer, and divinylbenzene （DVB） as crosslinker. The factors, which influence the selectivity of the polymers were explored. Effective separation was observed for racemic 4-phenyl-2-oxazolidinone in mobile phase of acetonitrile. The investigation of mobile phase suggested that the hydrogen bonds between template and functional monomer was a primary factor in chiral recognition, while the preparation of polymers implied that the л-л stacking interaction between template and crosslinker played a role in imprinting procedure.

关 键 词：Molecularly imprinted polymers （MIPs） 4-phenyl-2-oxazolidinone HPLC. 

分 类 号：O633.5[理学—高分子化学]