Study on Interaction of L-Tryptophan with p-Suffonatocalix[4]arene by Spectrofluorometry  

Study on Interaction of L-Tryptophan with p-Sulfonatocalix[4]arene by Spectrofluorometry

作　　者：Wen Ye LI Ying Li WEI Wen Ting AN Shao Min SHUANG Man Shing WONG 

机构地区：[1]School of Chemistry and Chelmcal Engmeenng, Shanxi University, Taiyuan 030006 [2]Department of Chemistry, Hong Kong Baptist University, Hong Kong

出　　处：《Chinese Chemical Letters》2006年第12期1592-1594,共3页中国化学快报（英文版）

基　　金：supported by the National Natural Science Foundation of China(No.20575038).

摘　　要：The interactions between L-tryptophan（L-Trp） and water-soluble p-sulfonatocalix[4]- arene （SCX4） were investigated by spectrofluorometry. The effect of pH was discussed. The interaction process was estimated from the thermodynamic viewpoint. The SCX4 was found to be able to adjust its conformation to fit the size of L-Trp, and the benzene of L-Trp penetrated into the hydrophobic cavity of SCX4. Meanwhile, the binding mechanism was further elucidated by IHNMR and molecular mechanics calculations.The interactions between L-tryptophan（L-Trp） and water-soluble p-sulfonatocalix[4]- arene （SCX4） were investigated by spectrofluorometry. The effect of pH was discussed. The interaction process was estimated from the thermodynamic viewpoint. The SCX4 was found to be able to adjust its conformation to fit the size of L-Trp, and the benzene of L-Trp penetrated into the hydrophobic cavity of SCX4. Meanwhile, the binding mechanism was further elucidated by IHNMR and molecular mechanics calculations.

关 键 词：L-TRYPTOPHAN arene fluorescence. 

分 类 号：O657.3[理学—分析化学] O625.7[理学—化学]