经动脉导管磁性微粒栓塞肿瘤的临床分析  

Clinical Analysis of Embolizing Tumor Using Magnetic Microsphere Through Artery Catheter

作　　者：程新宝[1] 袁曙光[2] 阎东[2] 

机构地区：[1]郑州市第五人民医院放射科,河南郑州450003 [2]昆明医学院附属第二医院放射科

出　　处：《实用放射学杂志》2006年第12期1500-1502,共3页Journal of Practical Radiology

摘　　要：目的探讨磁性微粒(Fe3O4)经动脉导管栓塞肿瘤机理与临床应用。方法采用Seld inger技术插管,用Fe3O4+5-Fu混悬药液栓塞94例肿瘤患者,其中5例肝癌栓塞后靶区外置磁场,15例栓后手术切除标本HE染色制片,25例栓塞1月后DSA复查,前后图像对照作统计学处理。结果病理提示肿瘤组织坏死彻底,栓塞前后DSA图像定量分析P值<0.05,临床观察栓后综合征明显下降。结论Fe3O4微粒是一种永久性栓塞颗粒,具有缓慢栓塞作用,对减少栓后临床并发症有一定作用。Objective To investigate the mechanism and the clinical value of magnetic microsphere （ Fe3O4 ） in embolizing tumor through artery catheter. Methods 94 patients with tumor were treated by embolized using Fe3O4 under fluoroscopy through catheters by Seldinger＇ s technique. Of them,5 cases of hepatocellular carcinoma underwent magnetic field putting on outside the target area, pathological examination was done in 15 cases,25 cases underwent DSA examination one month later and the DSA images before and after operation were analysed statistically. Results Pathological examination after embolism showed that necrosis of neoplastic tissue was 100 percent. The statistical analysis of DSA images was in P 〈 0.05. The complications caused by embolism significantly decreased. Conclusion Fe3O4 is good embolic substance and can avoid some complications by slow releasing embolism in treating tumors.

关 键 词：磁性微粒 动脉栓塞 肿瘤 介入放射学 

分 类 号：R7[医药卫生—临床医学] R815