胶原酶溶解术治疗颈椎间盘突出症的临床应用  

Clinical Application of Collagenase Chemonucleolysis in Treatment of Cervical Disc Herniation

作　　者：王义清[1] 朱大卫 任峰奇[1] 任莹[1] 夏樊军[1] 

机构地区：[1]西安市中心医院放射科,陕西西安710003 [2]陕西省铜川市人民医院放射科

出　　处：《实用放射学杂志》2006年第12期1506-1507,共2页Journal of Practical Radiology

摘　　要：目的介绍胶原酶溶解术治疗颈椎间盘突出症的操作方法并评价其疗效。方法20020-01-2004—12颈椎间盘突出症患者共92例，采用C6-7或C7～T1硬膜外穿刺，在X线机监控下，经穿刺针将微导管送至突出平面的硬膜外前侧间隙，成功后注入胶原酶1200～2400u。结果穿刺插管成功并注入胶原酶88例，其中80例经6～12个月随访，优良70例，优良率87．5％，未发生严重并发症。结论该治疗方法安全、有效，值得临床进一步研究和应用。Objective To introduce the method and to evaluate the therapeutic effect of collagenase chemonucleolysis for treatment of cervical disc herniation. Methods 92 patients with cervical herniated discs were selected from January 2002 to December 2004. The procedure was guided by DSA and the puncture was defined from C6.7 or C7 -T1 extradural cavity. Collagenase （ 1200 -2400 u ） was injcted in the herniated extradural cavity through the micrcatheter. Results The procedure of 88 cases was successful. 80 cases were followed up from 6 to 12 months. The effect showed that 70 cases（ 87.5% ） were excellent or good. No serious complication occurred. Conclusion The method of collagenase chemonucleolysis for treating cervical disc herniation is safe and effective,it can be used in clinic.

关 键 词：颈椎 椎间盘突出症 胶原酶 化学溶解术 

分 类 号：R681.53[医药卫生—骨科学] R815[医药卫生—外科学]