2型糖尿病合并冠心病患者冠状动脉造影及眼底荧光血管造影结果分析  

Analysis of coronary arteriographic and fluorescence fundus angiographic characteristics in type 2 diabetic patients with coronary heart disease

作　　者：宫建丽[1] 李文华[1] 孔香云[2] 唐侠[2] 张秀洲[1] 唐元升[1] 朱兴雷[1] 

机构地区：[1]山东省立医院老年及心血管内科,济南250021 [2]山东省立医院眼科,济南250021

出　　处：《中华内分泌代谢杂志》2006年第6期541-544,共4页Chinese Journal of Endocrinology and Metabolism

基　　金：山东省卫生科技发展计划(2003-35)

摘　　要：目的探讨2型糖尿病合并冠心病患者冠状动脉造影及眼底荧光血管造影的特点。方法对203例2型糖尿病合并冠心病患者的冠状动脉造影及眼底荧光血管造影结果,按照不同年龄或总胆固醇(TC)分组进行对比分析,并应用多因素logistic回归分析探讨影响血管造影特点的危险因素。结果不同年龄组之间随着年龄的增长,冠状动脉的单支血管病变比例降低,三支血管病变及左主干受累比例增高,视网膜病变亦增多并趋于严重,而其在TC异常组与TC正常组之间的差别无统计学意义；Logistic回归分析显示冠状动脉的病变程度与血糖、年龄、甘油三酯、性别等因素相关,视网膜病变程度与血糖和年龄相关。结论不同年龄组2型糖尿病合并冠心病患者的血管造影结果存在明显差异,年龄的增长能同时加重2型糖尿病合并冠心病患者的冠状动脉病变和视网膜病变。Objective To study the relationship between coronary arteriographic and fluorescence fundus angiographic characteristics in type 2 diabetic patients with coronary heart disease. Methods The study was carried out by the analysis of the data from coronary arteriography and fluorescence fundus angiography in 203 type 2 diabetic patients with coronary heart disease in different groups divided according to age or total cholesterol level. Logisitic regression analysis was applied to explore various risk factors to angiographic characteristics. Results With advancing age, there were more involvement of 3 coronary vessels or the left main branch along with stage Ⅲ retinopathy, but less single vessel diseases in the coronary arteries and less stage I retinopathy. The difference in coronary angiographic and fluorescence fundus angiographic characteristics between groups with different total cholesterol levels was not significant. Logistic regression analysis suggested that coronary artery diaease was related to age, sex and blood glucose and triglyceride levels while diabetic retinopathy was related to blood glucose level and age. Conclusion There is great difference in coronary arteriography and fluorescence fundus angiography among different age groups. Aging may aggravate the lesions both in the coronary arteries and fundal vessels in type 2 diabetic patients with coronary heart diseease.

关 键 词：糖尿病 2型 冠状动脉疾病 冠状动脉造影术 荧光素血管造影术 危险因素 

分 类 号：R587.1[医药卫生—内分泌] R541.4[医药卫生—内科学]