放射性液体球囊剂量分布的影响因素探讨  

Study on factors to influence dose distribution in radioactive liquid-filled balloon

作　　者：徐志勇[1] 张良安[2] 戴光复[2] 苑淑渝[2] 

机构地区：[1]复旦大学肿瘤医院放疗科,上海200032 [2]中国医学科学院放射医学研究所

出　　处：《中华放射医学与防护杂志》2006年第6期571-573,共3页Chinese Journal of Radiological Medicine and Protection

基　　金：国家自然科学基金资助项目(30170233)

摘　　要：目的研究放射性液体球囊在血管组织内剂量分布的影响因素。方法用模拟实验和理论计算两种方法估算注射压力对球囊的扩张能力、球囊内气泡、导管内核素对血液的不必要照射等影响因素。结果不同注射压力下球囊对血管组织产生的剂量不同,在压力大于4个大气压后,达到最大平衡。球囊内的气泡体积随着压力的增加而减少,对血管剂量的影响也变小。导管内的液体对血液组织有一定剂量的照射。结论用放射性球囊治疗患者时,注射压力、球囊内气泡和导管内的液体对剂量分布有影响。Objective To study factors to influence the dose distribution in radioactive liquid-filled balloon. Methods Dose distribution was estimated by simulation experiment and theory calculation to study the influences of injected pressure, an air bubble in balloon, and radioactive liquid in catheter. Results A balance was reached when the pressure was bigger than 4 standard atmospheres. The air bubble in balloon was reduced with increasing of the pressure. A certain exposure to blood was occurred due to radioactive liquid in catheter. Conclusions In treatment with radioactive liquid-filled balloon, the dose distribution are influenced by injected pressure, air bubble in balloon, and radioactive liquid in catheter.

关 键 词：放射性球囊 剂量点核函数 剂量分布 

分 类 号：R144[医药卫生—公共卫生与预防医学]