离退休体检人群认知功能检查的意义探讨  被引量：1

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class='type_ico_id'></b></a><a href='/zk/search.aspx?key=A%3d%5b%e5%90%b4%e9%b9%8f%5d' title='吴鹏[1]'>吴鹏[1]</a> <a href='/writer/article.aspx?id=100000011523247' target='_blank' ><b class='type_ico_id'></b></a><a href='/zk/search.aspx?key=A%3d%5b%e9%99%88%e7%91%9e%e5%86%ac%5d' title='陈瑞冬[1]'>陈瑞冬[1]</a> <a href='/writer/article.aspx?id=100000012259681' target='_blank' ><b class='type_ico_id'></b></a><a href='/zk/search.aspx?key=A%3d%5b%e8%8c%83%e5%9b%bd%e6%98%8e%5d' title='范国明[1]'>范国明[1]</a> <a href='/writer/article.aspx?id=100000016525100' target='_blank' ><b class='type_ico_id'></b></a><a href='/zk/search.aspx?key=A%3d%5b%e6%9d%8e%e6%82%a6%5d' title='李悦[1]'>李悦[1]</a> <a href='/writer/article.aspx?id=100000016473626' target='_blank' ><b class='type_ico_id'></b></a><a href='/zk/search.aspx?key=A%3d%5b%e5%ae%89%e5%b9%b3%e9%a1%ba%5d' title='安平顺[1]'>安平顺[1]</a> <a href='/writer/article.aspx?id=100000016627801' target='_blank' ><b class='type_ico_id'></b></a><a href='/zk/search.aspx?key=A%3d%5b%e9%82%b5%e5%b2%a9%5d' title='邵岩[1]'>邵岩[1]</a> <a href='/zk/search.aspx?key=A%3d%5b%e9%a9%ac%e7%ba%af%e6%ac%a3%5d' title='马纯欣'>马纯欣</a> <a href='/writer/article.aspx?id=100000016593693' target='_blank' ><b class='type_ico_id'></b></a><a href='/zk/search.aspx?key=A%3d%5b%e6%96%b9%e8%be%be%5d' title='方达[1]'>方达[1]</a> <a href='/writer/article.aspx?id=100000016504273' target='_blank' ><b class='type_ico_id'></b></a><a href='/zk/search.aspx?key=A%3d%5b%e6%ad%a6%e5%85%8b%e5%8d%8e%5d' title='武克华[1]'>武克华[1]</a> <a href='/zk/search.aspx?key=A%3d%5b%e5%8d%a2%e9%a3%8e%e7%8e%89%5d' title='卢风玉'>卢风玉</a> <em> </em></p><p class='organ'><strong>机构地区：</strong><a href='/organ/article.aspx?id=672199&subid=&showname=&searchtype=' target='_blank'><b class='type_ico_id'></b></a><a href='/zk/search.aspx?key=S%3d%e7%a7%a6%e7%9a%87%e5%b2%9b%e6%b8%af%e5%8f%a3%e5%8c%bb%e9%99%a2' title='[1]秦皇岛港口医院,河北秦皇岛066002'>[1]秦皇岛港口医院,河北秦皇岛066002</a> <em> </em></p><p class='from'><strong>出　　处：</strong><a href='/journal/summary.aspx?gch=81670X' target='_blank'><b class='type_ico_id'></b></a><a href='/zk/search.aspx?key=J%3d%5b%e8%80%81%e5%b9%b4%e5%8c%bb%e5%ad%a6%e4%b8%8e%e4%bf%9d%e5%81%a5%5d' title='老年医学与保健'>《老年医学与保健》</a>2006年第4期232-234,共3页<em>Geriatrics & Health Care</em></p><p class='abstrack'><strong>摘　　要：</strong>目的了解≥50岁离退休职工常规体检人群的认知功能状态，探讨常规体检中增加认知功能检查的意义。方法对2005年8月，10月在我院参与常规体检的秦皇岛港务局≥50岁的离退休职工进行面对面调查。调查分为筛查、复查诊断两个阶段。筛查用简易智能精神状态量表（MMSE）、Hachinski缺血评分、焦虑自评量表、抑郁自评量表；复查诊断用临床痴呆评定量表（CDR）、扩充痴呆量表（ESD）及记忆检查记录。轻度认知功能障碍（MCI）使用Perterson诊断标准、老年性痴呆（Alzheimer’s disease，以下简称AD）诊断标准使用美国国立神经和语言障碍和卒中——老年性痴呆及相关疾病学会（NINCDS-ADRDA）痴呆诊断标准。结果2269例体检者中，MMSE正常高分组1970人，占86．8％；正常低分126人。占5．6％。MCI70人，检出率3.1％；AD50人，均为轻度痴呆，检出率2．2％。血管性轻度认知功能障碍（VCI）36人。占1．6％。血管性痴呆（VaD）15人。占0．7％。混合性痴呆（MD）2人。占0．1％。各种异常项目检出率随年龄增加而增加。随文化程度的提高而减低。结论≥50岁常规体检人群可检出认知功能障碍，主要表现为MMSE正常低分、MCI和轻度AD。常规体检工作中增加认知功能检查有助于早期发现重点人群，既有利于早预防、早治疗．又便于管理，意义重大。<em>Objective To study the cognitive function state in retired people aged 50 years or over. Methods From august to October 2005, a total of 2269 retired people aged 50 years and over were investigated with two-stage survey. In screening survey, each participant was interviewed face to face with the Mini-Mental State Examination （MMSE）, Hachinski lskemic Scale（HIS）, SAS an＇d SDS. In diagnosing stage, those who had cognitive impairment were reassessed with Clinical Dementia Rating（CDR）, ESD. The clinical diagnoses of Mild Cognitive Impairment（MC1） and Alzheimer Disease（AD） were made respectively according to the Perterson＇s criteria and the, National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer Disease and Related Disorders Association （NINCDS-ADRDA） criteria. Results Among 2269 retired people, 2096 of normal MMSE scores （92.4%）, 70 of MCI（3.1%）, 50 of AD（2.2%）, 36 of VCI（1.6%）, 15 of VaD（0.2%）, 2 of MD（0.1%） were screened out. Conclusions The cognitive impairment was common in retired people aged 50 years and over. The prevalence of every abnormal state increases with aging and decreases with education.</em></p><p class='subject'><strong>关 键 词：</strong><a href='/zk/search.aspx?key=K%3d%5b%e8%ae%a4%e7%9f%a5%e9%9a%9c%e7%a2%8d%5d' title='认知障碍'>认知障碍</a> <a href='/zk/search.aspx?key=K%3d%5b%e7%ae%80%e6%98%8e%e7%b2%be%e7%a5%9e%e7%97%85%e7%8a%b6%e6%80%81%e8%af%84%e5%ae%9a%e9%87%8f%e8%a1%a8%5d' title='简明精神病状态评定量表'>简明精神病状态评定量表</a> <a href='/subject/article.aspx?id=2568286' target='_blank'><b class='type_ico_id'></b></a><a href='/zk/search.aspx?key=K%3d%5b%e4%bd%93%e6%a0%bc%e6%a3%80%e6%9f%a5%5d' title='体格检查'>体格检查</a> </p><p class='class'><strong>分 类 号：</strong><a href='/zk/search.aspx?key=C%3dR194.3' title='R194.3'>R194.3</a>[<a href = '/domain/article.aspx?id=449' >医药卫生—卫生事业管理</a>] </p> </div> <div id="content_wzxg" name="wzxg" class="article-graph"> <object width="695" height="250" classid="clsid:D27CDB6E-AE6D-11cf-96B8-444553540000" id="FlashID"> <param value="../flash/relation.swf" name="movie"> <param value="high" name="quality"> <param value="opaque" name="wmode"> <param value="6.0.65.0" name="swfversion"> <param value="dataUrl=/ajax/articlerelativegraph.ashx?id=23505963" name="flashVars"> <embed width="695" height="250" src="../flash/relation.swf" type="application/x-shockwave-flash" quality="high" wmode="opaque" flashvars="dataUrl=/ajax/articlerelativegraph.ashx?id=23505963"> </embed> </object> </div> <div class="article-relate-list"> <div class="relate-list"> <p id="ckwx_br"> </p> <h2 name="ckwx" id="ckwx">参考文献：</h2> <div id="listckwx"> <p class='submit'> <img src='/images/loading.gif' width='16' height='16' /> 正在载入数据... </p> </div> </div> <div class="relate-list"> <p id="2jckwx_br"> </p> <h2 name="2jckwx" id="2jckwx">二级参考文献：</h2> <div id="list2jckwx"> <p class='submit'> <img src='/images/loading.gif' width='16' height='16' /> 正在载入数据... </p> </div> </div> <div class="relate-list"> <p id="ohwx_br"> </p> <h2 name="ohwx" id="ohwx">耦合文献：</h2> <div id="listohwx"> <p class='submit'> <img src='/images/loading.gif' width='16' height='16' /> 正在载入数据... </p> </div> </div> <div class="relate-list"> <p id="yzwx_br"> </p> <h2 name="yzwx" id="yzwx">引证文献：</h2> <div id="listyzwx"> <p class='submit'> <img src='/images/loading.gif' width='16' height='16' /> 正在载入数据... </p> </div> </div> <div class="relate-list"> <p id="2jyzwx_br"> </p> <h2 name="2jyzwx" id="2jyzwx">二级引证文献：</h2> <div id="list2jyzwx"> <p class='submit'> <img src='/images/loading.gif' width='16' height='16' /> 正在载入数据... </p> </div> </div> <div class="relate-list"> <p id="tbywx_br"> </p> <h2 name="tbywx" id="tbywx">同被引文献：</h2> <div id="listtbywx"> <p class='submit'> <img src='/images/loading.gif' width='16' height='16' /> 正在载入数据... </p> </div> </div> <div class="relate-list"> <p id="xgqklw_br"> </p> <h2 name="xgqklw" id="xgqklw">相关期刊文献：</h2> <div id="listxgqklw"> <p class='submit'> <img src='/images/loading.gif' width='16' height='16' /> 正在载入数据... </p> </div> </div> </div> </div> <div class="article-about"> <div class="about-box"> <h5 class="name">相关的主题<tt><a class="hide" href="#"></a></tt></h5> <div class="about-list"> </div> </div> <div class="about-box"> <h5 class="name">相关的作者对象<tt><a class="" href="#"></a></tt></h5> <div class="about-list" style="display: none;"> </div> </div> <div class="about-box"> <h5 class="name">相关的机构对象<tt><a class="" href="#"></a></tt></h5> <div class="about-list" style="display: none;"> </div> </div> </div> </div> </div> <script type="text/javascript" src="/scripts/articlerelation.min.js"></script> <script type="text/javascript" src="/scripts/articlerightrelation.min.js"></script> <script type="text/javascript" src="/scripts/articledown.min.js"></script> <div class="layer-box download" id="downloadlayer" style="display: none"> <div class="close"> <a onclick="closedown()" href="javascript:void(0)"> <img src="/images/layer-close.png" width="21" height="21" alt="" /> </a> </div> <h5 class="layer-title">下载全文</h5> <div id="downloadinfo"></div> </div> <div class="layer-box download" id="downloadlayer2" style="display:none;min-height:100px;width:500px;"> <p> <img src="/images/loading2.gif" width="64" height="64"> <span style="font-size:20px;vertical-align:middle;padding-bottom:50px;">正在链接到云南高校图书馆文献保障联盟下载...</span> </p> </div> <script id="bdshare_js" data="type=tools&uid=0" type="text/javascript"></script> <script type="text/javascript"> $(function () { var rd = GetQueryString("rd"); 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