早产母乳中淀粉酶活性观察  

Amylase in preterm human milk.

作　　者：钱继红[1] 吴圣楣[1] 陶美华[2] 陆伟明[3] 王蓓[3] 朱建幸[1] 

机构地区：[1]上海交通大学医学院附属新华医院儿内科,200092 [2]上海交通大学医学院附属新华医院检验科,200092 [3]上海交通大学医学院附属新华医院产科,200092

出　　处：《中国新生儿科杂志》2006年第6期324-327,共4页Chinese Journal of Neonatology

摘　　要：目的观察不同哺乳阶段早产儿母乳中淀粉酶活性变化,并与足月儿母乳作比较。方法测定36例早产儿乳母和40名足月儿乳母不同泌乳期母乳中淀粉酶活性。结果早产儿乳母其初乳淀粉酶活性较高,为10232.93±1·48IU/L,随着泌乳期的延长,淀粉酶活性逐渐下降。与足月儿母乳相似,早产儿母乳淀粉酶98%为唾液型淀粉酶。不同胎龄早产儿其母乳淀粉酶活性均值较接近,差异无统计学意义。分别比较早产和足月母乳在各泌乳阶段的淀粉酶活性显示,在任何一阶段,早产母乳淀粉酶活性的绝对值略高于足月母乳,但差异无统计学意义,P均>0·05。结论早产儿母乳含有较高活性的淀粉酶,对早产儿的淀粉消化和潜在的抗感染作用具有重要意义,应鼓励对早产儿进行母乳喂养。Objective To explore the dynamic changes of amylase in preterm human milk and analyse the difference of amylase activity between preterm and term human milk. Methods The amylase activities in the milk from 36 mothers of preterm infants and 40 mothers of term infants were measured at different periods of lactation. Results There was a high amylase activity in preterm colostrums （10 232.92±1.48IU/L）, which gradually decreases during the first 6 weeks after delivery. The isoamylase of preterm milk was exclusively of the salivary type, just as in term milk. Compared with term milk, amylase activity of preterm human milk in each period of lactation was slightly higher. But no significant difference of amylase activity could be found between preterm and term human milk （P 〉0. 05）. Conclusions Preterm human milk is rich in amylase, which contributes to the preterm infant＇s ability to digest starch and potential antibacterial role. Breast-feeding is worthy to be recommended in preterm infants.

关 键 词：婴儿 早产 母乳 淀粉酶类 

分 类 号：R174.4[医药卫生—妇幼卫生保健]