自然和热凝固的人肝组织对KTP/YAG激光的光学特性的比较研究  

Comparison Study of Optical Properties of Native and Coagulated Human Liver Tissue at KTP/YAG Laser in vitro

作　　者：魏华江[1] 许静芬[2] 何博华[3] 李晓原[4] 巫国勇[5] 张薇[2] 

机构地区：[1]华南师范大学激光生命科学研究所,广东广州510631 [2]广东药学院基础学科部,广东广州510224 [3]广东药学院临床医学系外科,广东广州510224 [4]中山大学医学院激光医学研究室,广东广州510089 [5]中山大学医学院第一附属医院心胸外科,广东广州510089

出　　处：《激光生物学报》2006年第6期588-593,共6页Acta Laser Biology Sinica

基　　金：广东药学院资助项目(43543020;J5646048;G9640020)

摘　　要：本文采用双积分球测量系统和Inverse Add ing-Doub ling方法,研究了自然和热凝固的人肝组织对532nm的KTP激光和1 064 nm的Nd:YAG激光的光学特性。结果表明:热凝固的人肝组织对532 nm的KTP激光的吸收系数较自然的肝组织的吸收系数增大了23.5%(P<0.05),热凝固的肝组织对1 064 nm的Nd:YAG激光的吸收系数较自然的肝组织的吸收系数减小了34.3%(P<0.05)。热凝固的人肝组织对532 nm的KTP激光的散射系数较自然的肝组织的散射系数增大了4.50倍(P<0.05),热凝固的肝组织对1 064 nm的Nd:YAG激光的散射系数较自然的肝组织的散射系数增大了6.41倍(P<0.05)。热凝固的人肝组织对532 nm的KTP激光的各向异性因子较自然的肝组织的各向异性因子减小了5.47%,热凝固的肝组织对1 064 nm的Nd:YAG激光的各向异性因子较自然的肝组织的各向异性因子减小了1.95%。A double-integrating-spheres system and Inverse Adding-doubling method were used in this experiment. The optical properties of native and coagulated human liver tissue at 532 nm and 1 064 nm of KTP/YAG laser were study. The results of experiment showed that there is a 23.5 percent increase in the absorption coefficient for coagulated human liver tissues at 532 nm of KTP laser in comparison with the absorption coefficient for native human liver tissues at the same laser wavelength （ P 〈 0.05 ） , and there is a 34.3 percent decrease in the absorption coefficient fiw coagulated human liver tissues at 1 064 nm of Nd ： YAG laser in comparison with the absorption coefficient for native human liver tissues at the same laser wavelength （ P 〈 0.05 ）. There is a 4.50 times increase in the scattering coefficient for coagulated human liver tissues at 532 nm to compare with the scattering coefficient for native human liver tissues at the same laser wavelength （ P 〈 0.05 ）, and there also is a 6.41 times increase in the scattering coefficient for coagulated human liver tissues at 1 064 nm to compare with the scattering coefficient for native human liver tissues at the same laser wavelength （ P 〈 0.05 ）. there is a 5.47 percent decrease in the anisotropy factor for coagulated human liver tissues at 532 nm to compare with the anisotropy factor for native human liver tissues at the same laser wavelength （ P 〈 0.05 ）, and there also is a 1.95 percent decrease in the anisotropy factor for coagulated human liver tissues at 1 064 nm to compare with the anisotropy factor for native human liver tissues at the same laser wavelength （ P 〈 0.05 ）.

关 键 词：人肝组织 KTP/YAG激光 热凝固 光学特性 

分 类 号：R318.51[医药卫生—生物医学工程]