微波辐射催化合成氯乙酸异丙酯  

Catalytic Synthesis of Isopropyl Chloroacetate under Microwave Irradiation

作　　者：兰翠玲[1] 谭华征 

机构地区：[1]百色学院化学与生命科学系,广西百色533000 [2]北京凯因生物技术有限公司,北京100176

出　　处：《广东化工》2006年第12期42-44,共3页Guangdong Chemical Industry

摘　　要：在微波辐射下,以稀土固体超强酸SO42-/TiO2/La3+为催化剂合成氯乙酸异丙酯。考察微波输出功率、反应时间、催化剂用量、酸醇的物质的量比等因素对反应的影响。通过实验得出合成氯乙酸异丙酯的最佳反应条件是:氯乙酸和异丙醇的物质的量比为1∶2.5,催化剂用量为0.5g,微波输出功率为729W,反应时间为12min,在此反应条件下,氯乙酸的酯化率为95.6%。Isopropyl chloroacetate is synthesized from chloroacetic acid and isopropyl alcohol with rare earth solids upper acid SO4^2-/ TiO2/ La^3＋ as catalysts under the irradiation of microwave. It is investigated that the effects of microwave irradiation power（P）, reaction time（T）, the amount of catalyst and molar ratio of acid-alcohol on the process. The optimum operation conditions are obtained by experiment and are as follows： the mole ratio of chloroacetic acid and isopropyl alcohol is 1：2.5 （mol / mol ）, the amount of catalyst is 0.5 g, irradiation power 729 W, reaction time 12 min. Under above conditions, 95.4% of chloroacetic acid is converted, the yield chloroacetates is 89.4%.

关 键 词：微波辐射 氯乙酸异丙酯 SO4^2-/TiO2/La^3+稀土固体超强酸 合成 

分 类 号：TQ225.3[化学工程—有机化工]