氟哌酸锌凝胶剂的制备及质量控制  

Preparation and quality control for mastic of zinc norfloxacine

作　　者：谭先红[1] 陈国良[1] 张善堂（编审） 

机构地区：[1]安徽省立医院产科,合肥230001 [2]不详

出　　处：《安徽卫生职业技术学院学报》2006年第6期70-71,共2页Journal of Anhui Health Vocational & Technical College

摘　　要：目的:研制一种局部应用治疗小儿湿疹的制剂。方法:按凝胶剂制备工艺制备了诺氟沙星锌凝胶剂;建立了性状、鉴别、酸碱度、含量测定等质控方法,并进行了体外抑菌实验。结果:以紫外分光光度法测定诺氟沙星锌凝胶剂的含量,平均回收率为100.03%,RSD为1.67%;稳定性良好。结论:该制剂制备工艺可行,性质稳定,质控方法简单可靠。Objective To develop one kind of partial preparation to treat the young child eczema. Methods According to mastic preparation craft mastic of zinc norfloxacin was made and some methods like the character, the distinction and the potential of hydrogen were put forward and external inhibition bacterium experiment was performed. Results The content of the mastic of zinc norfloxacin was determind by UV spectrophotometer. The rate of average recovery was 100.03%, RSD was 1.67%.This mastic had a good stablility. Conclusion The preparation method is available .The property of mastic is stable .Those quality control standards are reliable.

关 键 词：诺氟沙星锌 凝胺剂 制备方法 质控标准 

分 类 号：R986[医药卫生—药品]