布托啡诺复合罗哌卡因用于术后硬膜外病人自控镇痛  

Postoperative PCEA with butorphanol plus ropviacaine

作　　者：周全军[1] 张小洺[1] 姚尚龙[1] 

机构地区：[1]华中科技大学同济医学院附属协和医院麻醉学教研室,武汉市430022

出　　处：《国际麻醉学与复苏杂志》2006年第6期341-343,共3页International Journal of Anesthesiology and Resuscitation

摘　　要：Objective To observe the analgesia and side effects of butorphanol or morphine combined with ropivacaine in postoperative patients with controlled epidural analgesia(PCEA).Methods 100patients,undergoing abdominal hysterectomy with contious epidural anesthesia,were randomly divided two groups.Butorphanol 15 mg/L(experiment groups) or morphine 20 mg/L(control groups) with 1.5 g/L ropivacaine were given epidurally after surgery respectively.Postoperative pain was assessed using VAS.The patients’ satisfaction level and adverse events were also recorded.Results the VAS scores of study group were significantly lower than control group at 2 h and 8 h after operations.The incidences and degree of nausea and vomiting of study group were lower than control group when patients were in state of rest or coughing respectively(P<0.05).The number of effective consumption in study group was significantly less than that in control group. Conclusion 15 mg/L butorphanol with 1.5 g/L ropivacaine could be safe in PCEA after abdominal hysterectomy.Butorphanol had better analgesic effect than morphine,with less side effects.Objective To observe the analgesia and side effects of butorphanol or morphine combined with ropivacaine in postoperative patients with controlled epidural analgesia （PCEA）. Methods 100patients, undergoing abdominal hysterectomy with contious epidural anesthesia, were randomly divided two groups. Butorphanol 15 mg/L （experiment groups） or morphine 20 mg/L （control groups） with 1.5 g/L ropivacaine were given epidurally after surgery respectively. Postoperative pain was assessed using VAS. The patients＇ satisfaction level and adverse events were also recorded. Results the VAS scores of study group were significantly lower than control group at 2 h and g h after operations. The incidences and degree of nausea and vomiting of study group were lower than control group when patients were in state of rest or coughing respectively （P 〈 0.05）. The number of effective consumption in study group was significantly less than that in control group. Conclusion 15 mg/L butorphanol with 1.5 g/L ropivacaine could be safe in PCEA after abdominal hysterectomy. Butorphanol had better analgesic effect than morphine, with less side effects.

关 键 词：硬膜外病人自控镇痛 罗哌卡因 术后镇痛 长效酰胺类局麻药 病人自控硬膜外镇痛 心血管系统毒性 硬膜外连续输注 麻醉药联合应用 

分 类 号：R614.42[医药卫生—麻醉学]