顿服普罗帕酮联合电复律转复持续性心房颤动的临床观察  

Clinical effect of propafenone combined with electrical cardioversion in converting persistent atrial fibrillation

作　　者：马丹[1] 刘凤岐[1] 富路[1] 孙峻峰[1] 李元十[1] 

机构地区：[1]哈尔滨医科大学第一临床医学院心内三科,黑龙江哈尔滨150001

出　　处：《哈尔滨医科大学学报》2006年第6期502-504,共3页Journal of Harbin Medical University

摘　　要：目的探讨普罗帕酮联合电复律转复持续性心房颤动的效果。方法30例持续性房颤患者电复律前服用负荷量普罗帕酮,房颤转复服用小剂量普罗帕酮100mg,每天3次维持。结果29例患者均转为窦性心律,2例患者转复后窦性心律不能维持,早期有效率为90%。随访(12.3±2.0)月,期间5例(18.5%)复发,总体73.3%维持窦性心律。结论普罗帕酮联合电复律是治疗持续心房颤动的有效方法。Objective To study the effect of propafenone combined with electrical eardioversion in converting persistent atrial fibrillation. Methods Thirty patients with persistent atrial fibrillation underwent a loading dose of propafenone administration before electrical cardioversion, then the patients receive propafenone maintenance therapy. Results Twenty-nine patients were converted to sinus rhythm, of these, sinus rhythm can not be maintained in two cases,so the early effecive rate was 90% ,during the follow-up survey period of （12.3 ± 2.0） month,5 cases（18.5%） were recurrence,so the total maintenance rate of sinus rhythm was 73.3%. Conclusion Propafenone combined with electrical cardioversion may provide an effective therapy in converting persistent atrial fibrillation.

关 键 词：心房颤动 普罗帕酮 心脏复律 直流电 

分 类 号：R541.75[医药卫生—心血管疾病]