超促排卵对子宫内膜容受性影响的研究进展  

Progress in research on impact of controlled ovarian hyperstimulation on endomertial receptivity

作　　者：孙玉英[1] 陈少春[1] 王素霞[1] 

机构地区：[1]浙江中医药大学,浙江杭州310053

出　　处：《中国妇幼健康研究》2006年第6期519-521,共3页Chinese Journal of Woman and Child Health Research

摘　　要：尽管控制性超排卵治疗较其它促排卵方案理想,但是控制性超排卵仍然对子宫内膜容受性有影响,使胚胎着床发生障碍,妊娠率降低。控制性超排卵主要是影响子宫内膜容受性标志性因子整合素、白血病抑制因子、转化生长因子以及子宫内膜容受性的形态学标记胞饮突的生长发育,并使子宫内膜雌孕激素受体降调不良,干扰内源性激素水平,进而影响临床妊娠率。Controlled ovarian hyperstimulation （COH） is an important assisted reproductive technique （ART）. Although it may be more advisable than other techniques, it affects endometrial receptivity, which may disturb implantation of ovum and reduce pregnancy rate. COH mainly affects marker factors of endometrial receptivity such as integrins, leukemia inhibitory factor, transforming growth factor and development of its morphological marker pinopodes. COH also makes estrogen receptor and progestogen receptor poorly down - regulated, so it disturbs hormone level in body and affects the pregnancy rate. In this article, we reviewed progress in research on impact of controlled ovarian hyperstimulation on endomertial receptivity.

关 键 词：控制性超排卵 子宫内膜客受性 整合素 胞饮突 

分 类 号：R713.7[医药卫生—妇产科学]