二乙三胺五乙酸的合成  

Synthesis of diethylenetriamine pentaacetic acid

作　　者：韩利 刘伟琪 王庆 

机构地区：[1]抚顺市化工研究设计院,辽宁抚顺113006

出　　处：《化学工业与工程技术》2006年第6期24-25,共2页Journal of Chemical Industry & Engineering

摘　　要：以氰化钠、甲醛及二乙三胺为原料合成了二乙三胺五乙酸。适宜的工艺条件为：反应温度95℃,空气流量0．5 L/min,n_(二乙三胺)∶n_(氰化钠)∶n_(甲醛)=1∶5．1∶5．25(物质的量比)；优选盐酸为酸化试剂,pH =1．2～1．9,合成液中二乙三胺五钠盐的最佳质量分数为20%,二乙三胺五钠盐的酸化收率达到80%。此工艺条件温和、易控。Diethylenetriamine pentaacetic acid(DTPA)is syn- thesized by sodium cyanide,formaldehyde and diethylenetriamine. The optimum conditions are as follows:the reaction temperature is 95℃,the molar ratio of NH(CH_2CH_2NH_2)_2 to NaCN and CH_2O is 1:5.1:5.25,the optimum acidification reagent is HCl, the pH value isl.2～1.9,and the mass fraction of dicthylenetri- amine penta-sodium acetate in the solution is 20%.The conditions are moderate and easy to control,and the yield of DTPA can reach to 80%.

关 键 词：二乙三胺五乙酸 合成 氰化钠法 

分 类 号：TQ225.12[化学工程—有机化工]