家蚕蛋白质组研究现状与趋势  

The Present Situation and Trend of Proteome Research in Silkworm,Bombyx mori

作　　者：王永强[1] 靳远祥[2] 何秀玲[1] 徐孟奎[3] 孟智启[1] 

机构地区：[1]浙江省农业科学院蚕桑研究所,杭州310021 [2]浙江工业大学生物与环境工程学院,杭州310014 [3]浙江大学动物科学学院,杭州310029

出　　处：《蚕业科学》2006年第4期543-549,共7页ACTA SERICOLOGICA SINICA

基　　金：浙江省自然科学基金项目(编号M303458);教育部留学回国基金项目。

摘　　要：蛋白质组研究是在蛋白质水平定量、动态、整体研究生物体,由此可获得疾病过程、细胞生理生化过程以及调控网络的相关信息。家蚕是鳞翅目昆虫的模式生物,随着蛋白质组学、生物信息学的迅速发展和家蚕全基因组序列的测定完成,家蚕蛋白质组研究方面也逐步展开,已在家蚕丝腺、雌性附腺、胚胎、血液及中肠蛋白质组的研究方面取得进展。利用差异蛋白质组学技术发现家蚕重要经济性状相关的功能蛋白,并探明其作用机制及调控模式,则是今后的主要研究方向。Proteome research is to undestand quantitatively, dymamically and wholly the organism on the protein level through which the relative informations about disease, physiology and biochemistry of the cell and regulation can be gained. Silkworm is the model organism of lepidopteran insects and its proteome study is also gradually carried out along with the rapid development of proteomics and bioinformatics and sequenced completion of silkworm total genome. Progress of proteomics about silk gland, female colleterial gland, embryo, hemolymph and midgut was achieved. It is the major researoh field in future to find functional protein related to the important economic characters of the silkworm and reveal its action mechanism and regulation mode by using differential proteomics techonology.

关 键 词：家蚕 蛋白质组 功能蛋白 调控机制 

分 类 号：Q966[生物学—昆虫学] S881.2[农业科学—特种经济动物饲养]