国产与进口头孢吡肟治疗急性泌尿系统感染的成本-效果分析  

Cost-effectiveness analysis of domestic and imported cefepime in treatment of acute urinary infections

作　　者：李国成[1] 陈清霞[1] 陈广惠[1] 杨鸿[1] 

机构地区：[1]中山大学附属第二医院,广州510120

出　　处：《重庆医学》2006年第24期2261-2262,共2页Chongqing medicine

摘　　要：目的比较国产与进口头孢吡肟治疗急性中重度泌尿系统感染的经济效果。方法将122例病例随机分为两组,A组(使用国产药)61例,B组(使用进口药)61例,运用药物经济学方法进行成本-效果分析。结果A、B两组治疗方案的有效率分别为98．36％和96．72％,致病菌清除率均接近100％,两组药物不良反应发生率分别为6．56％和10．47％。两组对比差异均无统计学意义(P＞0．05)。成本-效果比(C／E)分别为4059．64和4625．45,与国产头孢吡肟组相比,进口头孢吡肟组每增加一个单位效果需多花费29309．74元。结论综合考虑,国产头孢吡肟对泌尿系统感染的经济效果优于进口药。Objective To compare the cost-effectlveness between domestic and imported cefepime in the treatment of acute urinary infections. Methods One hundred and twenty patients were randomly divided into 2 groups. There were 61 cases in domestic group（A group） and 61 cases in imported group （B group）, Principle of pharmacoeconomies was adopted to analyze cost effectiveness. Results The effective rates of A group and B group were 98.36% and 96.72% ,the bacterial eradiction rate both was 100 %, and the incidence of adverse reaction was 6.56% and 10.47% respectively. The difference was not significant between two groups （P〉0.05）. The cost-effectiveness ratio（C/E） were 4 059.64 and 4 625.45 respectively. The cost for every one unit increment of effectiveness for B group was RMB 29 309.76 yuan more than that of A group. Conclusion Taking everything into consideration, the economical effects of domestic cefepime was better than imported cefepime in the treatment of acute urinary infections.

关 键 词：头孢吡肟 泌尿系统感染 成本-效果分析 

分 类 号：R691.3[医药卫生—泌尿科学]