痛通贴剂制备工艺的考察  

EXPERIMENTAL STUDIES ON THE PREPARATION TECHNIQUES OF TONGTONG PATCH

作　　者：张芳侠 高振珅[2] 姚运香[2] 苏嘉伟[2] 

机构地区：[1]陕西省中药研究所,陕西咸阳712000 [2]陕西科技大学生命科学与工程学院,陕西咸阳712081

出　　处：《陕西科技大学学报（自然科学版）》2006年第6期70-72,共3页Journal of Shaanxi University of Science & Technology

基　　金：咸阳市科技局项目(K05012-4);陕西科技大学研究生创新基金项目(yc05-6)

摘　　要：采用正交试验设计方法,以贴剂的外观、膏体的均匀性、可涂展性、膜残留性、对皮肤的追随性、粘度、剥离强度等为综合考察指标,对贴剂基质成型工艺进行了实验研究,并对制成的贴剂进行了质量考察,优选出痛通贴剂的制备工艺:搅拌时间20min;炼合温度60℃;胶粘剂组分先与交联剂组分混合,最后再加入填充剂组分。该痛通贴剂配方合理,制备工艺简便易行,质量可控。Orthogonal design was used to observe the adhesion power, the stability to the skin, the homogeneity ,layer residue , flexibility and adhesive ability of the patch. To establish the optimum preparation procedure for Tongtong Patch. The optimized procedures were stirring for 20minute, plaster at 60℃, and after mixing the excipients and the bonds, then adding filling material. The formulation of Tongtong Patch is resonable and its preparation is simple and rapid.

关 键 词：痛通贴剂 正交试验 工艺研究 

分 类 号：R283.3[医药卫生—中药学]