复方甲氧那敏胶囊治疗轻中度支气管哮喘  

Compound Methoxyphenamine Capsules Treat Asthma with Mild to Moderate Degree

作　　者：李善群[1] 吴小丹[1] 黄建浩[1] 钮善福[1] 白春学[1] 

机构地区：[1]复旦大学附属中山医院肺科,上海200032

出　　处：《中国临床医学》2006年第6期918-919,共2页Chinese Journal of Clinical Medicine

摘　　要：目的：评价国产复方甲氧那敏胶囊治疗轻中度支气管哮喘的临床疗效和安全性。方法：40例患者随机分为国产复方甲氧那敏胶囊治疗组和阿斯美胶囊对照组,观察治疗前后咳嗽、喘息、实验室指标、肺通气功能(PEF)指标和不良反应。结果：即刻疗效的评价：治疗组与对照组的临控率、显效率分别为65．0%、90．0%；连续疗效的评价：治疗组与时照组的临控率及显效率分别为75．0%及85%。两组患者治疗前后血压及各项实验室指标均无明显改变。治疗组与对照组不良反应的例数分别为3例和2例,发生率分别为15．0%、10．0%,治疗组有1例发生嗜睡(5%),治疗组与对照组分别有1例出现头晕(5%),治疗组有1例出现胃部不适(5%),对照组有1例出现心跳加快(5%)。结论：国产复方甲氧那敏胶囊具有较好的临床治疗作用,且有良好的安全性,值得临床推广。Objective：To evaluate the clinical efficacy and safety of compound methoxyphenamine manufactured in China in the treatment of asthma with mild or moderate degree. Methyls：40 patients were randomly divided into two groups, compound methoxyphenamine treat group and Asmeton capsule control group,we evaluated every marker about cough, gasp, some laboratory test , pulmonary function test（PEF） and side-eaction. The duration of treatment was 7 days. Results： Effect at once ： clinic effect rate were treating group 65.0%, control group 90% ,continuous effect rate were treating group 75.0%, comrol group 85%. The physical examination and laboratory test had not any changed during 7 days. Conclusion： Compound methoxyphenamine has reliable curative effect and good safety in the treatment of mild to moderate asthma.

关 键 词：复方甲氧那敏 支气管哮喘 疗效 安全性 

分 类 号：R562.25[医药卫生—呼吸系统]