怀疑原发性脑干损伤早期死亡脑干纤维联结蛋白的免疫组化研究  

Brain-Stem Fibronectin Studies Immunohistochemically in Early Dying Cases of Suspected Primary Brain-Stem Injury

作　　者：周伟[1] 祝家镇[1] 徐小虎[1] 

机构地区：[1]中山医科大学法医病理教研室

出　　处：《法医学杂志》1996年第4期200-201,共2页Journal of Forensic Medicine

摘　　要：在本研究的１３个案例中，怀疑原发性脑干伤死亡的５例，明确死因的８例，其中严重闭合性颅脑损伤２例；缢死１例，失血性休克１例，电击２例，海洛因中毒２例。用ＬＳＡＢ法对１３例脑干的中脑、脑桥、延髓各部ＦＮ进行检测。结果显示５例怀疑为原发性脑干伤、２例严重颅脑损伤、２例海洛因中毒死者的脑千部位的神经元内均可见ＦＮ的异常沉积，其它各例未见ＦＮ的异常沉积。结果表明；ＬＳＡＢ－ＦＮ法是诊断原发性脑干伤早期死亡灵敏但非特异的形态学指标。In the thirteen cases studied below. five are suspected primary brain-stem injury,the other eight are clear in the cause of death,including severe closed craniocerebral injury(2 cases),hanging(1 case),hemorrhagic shock(1 case),death from electricity(2 cases) and heroin poisoning(2 cases).FN in brain-stem (midbrain pons and medullary bulb) is detected in some brain-stem neurons in all cases of the suspected primary brain-stem injury, severe craniocerebral injury and beroin poisoning.Thus LSAB-FN method is not specific but very sensitive morphologic parameter of primary brain-stem injury

关 键 词：纤维联结蛋白 免疫组化 原发性 脑干损伤 死亡 

分 类 号：R89[医药卫生—法医学] R651.15[医药卫生—临床医学]