雷公藤药材中雷公藤甲素变异规律  

Study on content variation of triptolide in medicinal material of Tripterygium

作　　者：斯金平[1] 黄文华[2] 郭宝林[2] 阮秀春 李世洁[2] 

机构地区：[1]浙江林学院,浙江临安311300 [2]中国医学科学院中国协和医科大学药用植物研究所,北京100094 [3]浙江省丽水市林业科学研究所,浙江丽水323000

出　　处：《中国中药杂志》2006年第24期2026-2030,共5页China Journal of Chinese Materia Medica

基　　金：浙江省自然科学基金项目(Y205031);浙江省林业厅重大科技计划(2002A01)

摘　　要：目的：研究雷公藤药材中雷公藤甲素质量分数的变异规律,为雷公藤药材人工栽培遗传改良、采收加工、质量评价、产区区划提供理论依据。方法：HPLC测定雷公藤甲素质量分数。结果：给出了雷公藤药材中雷公藤甲素质量分数与种质、生长年限、采收季节的关系。结论：雷公藤药材木质部雷公藤甲素质量分数显著地受遗传因素的影响,而根皮受遗传因素的影响不明显；雷公藤甲素的积累需要一定的年限,但超过一定的年限,随着木质部次生代谢能力的由盛转衰而下降；木质部雷公藤甲素质量分数在冬季最高,生长季节明显下降；根皮雷公藤甲素质量分数受季节的影响较小,规律不明显。Objective： To study the content variation of triptolide in medicinal material of Tripterygium and provide theoretical basis for the hereditary improvement, the gathering and process, the quality evaluation and the provenance division in medicinal material of Tripterygium. Method： HPLC method was used to determine the content of triptolide. Result： The relations between triptolide and germplasm, growth year, gathering season were found out basically. Conclusion： The triptolide contents in xylem are affected by hereditary factors remarkably. While the triptolide contents in phloem are not affected obviously. The accumulation of triptolide needs the certain growth years. However when growth is beyond certain years, the triptolide content decreases with the disintegration of secondary metabolism in xylem. The triptolide in xylem is highest in winter and decreasing in growing season. The triptolide in phloem is less affected by the season.

关 键 词：雷公藤 雷公藤甲素 种质 采收年龄 采收季节 

分 类 号：R284.1[医药卫生—中药学] S567[医药卫生—中医学]