维生素C对快大型黄羽肉鸡肺动脉高压综合征的影响  

Effect of Vitamin C on Pulmonary Hypertension Syndrome in Fast-growing Yellow Broilers

作　　者：臧莹安[1] 丁发源[1] 王小龙[2] 

机构地区：[1]广东省农业科学院畜牧研究所,广东广州510640 [2]南京农业大学动物医学院,江苏南京210095

出　　处：《中国家禽》2006年第24期103-105,109,共4页China Poultry

基　　金：中国博士后科学基金资助项目(编号2003033411)

摘　　要：采取分组对比的方法(对照组,肺动脉高压综合征(PHS)发病组,维生素C治疗组)分别检测试验鸡只肝组织、肠黏膜、心肌线粒体中的NO含量和NOS的活性。结果显示,对于发生PHS的快大型黄羽肉鸡,其肝脏、心肌和肠黏膜线粒体NO含量呈现先显著上升后显著下降的变化趋势(P<0.05)。线粒体NOS活力的变化趋势则与NO一致。与对照组相比,维生素C治疗组各指标则呈现相反的变化,说明其能有效地阻止快大型黄羽肉鸡发生PHS这一过程。A total of 120 fast-growing Yellow broilers were divided randomly into three groups that were respectively treated as healthy group,pulmonary hypertension syndrome （PHS） group and Vitamin treatment group. The liver,cardiac muscle and mucous membrane of intestine were taken from 6 broilers per one group. Concentrations of nitrix oxide（NO） and activity of acnitric oxide synthase（NOS） of mitoehondria were measured. The results indicated that at first NO and NOS level of the mitochondria in liver,cardiac muscle and intestinal mucous membrane increased significantly （P〈0,05）. Then NO and NOS level of those decreased significantly （P〈0.05）. After treatment of vitamin C,all these indexes changed following opposite way. It was obvious that vitamin C was efficient for controlling PHS.

关 键 词：快大型黄羽肉鸡 肺动脉高压综合征 线粒体 NO NOS 

分 类 号：S858.316.2[农业科学—临床兽医学]