大剂量丙种球蛋白佐治毛细支气管炎的临床观察  

The clinic observation of the large does γ-globulin on patients with bronchiolitis

作　　者：宁静[1] 魏培忠[1] 夏宇靖[1] 杨瑄[1] 

机构地区：[1]天津市儿童医院呼吸科,天津300074

出　　处：《天津医科大学学报》2006年第4期563-565,共3页Journal of Tianjin Medical University

摘　　要：目的:评价大剂量丙种球蛋白在毛细支气管炎治疗中的应用价值。方法:按随机抽样法分对照组和大剂量丙种球蛋白(IVIG)组。大剂量IVIG组(45例)在常规治疗基础上加用IVIG每次1.0g/kg,连用2d,观察疗效;对照组(49例)给予常规治疗。病愈后对其随访。结果:大剂量IVIG组在改善症状、消除肺部体征及缩短住院时间和提高治愈率等方面明显优于对照组(P<0.01)。随访50例反复喘息发作患儿,大剂量IVIG组反复喘息发生率占31.1%,对照组占73.5%,有显著性差异(P<0.01)。结论:大剂量IVIG佐治毛细支气管炎有明显疗效,并能减少病愈后反复哮喘发作。Objective： To investigate the value of large doesγ-globulin（IVIG） on patients with bronchiolitis. Methods： The patients were randomly divided into control group general treatment and large does IVIG group general treatment with IVIG 1.0 g/kg for 2 days. The effect was followed up after cure. Results： The large does IVIG group were significantly more efficient than the control group in aspects that resulted long objective. Shortening length of stay and elevating care rate （P〈0.01）. Followed-up 50 infant patients with gasping repeated, the incidence of gasp in the large close IVIG group （31.1%） and the control group （73.5%） was significantly different （P〈0.01）. Conclusion： Large does IVIG used in bronchiolitis has better therapeutic effect and no adverse reaction

关 键 词：婴儿 毛细支气管炎 丙种球蛋白 

分 类 号：R725.6[医药卫生—儿科]