冠心病患者合并2型糖尿病及高血压病对冠状动脉病变的影响  

Influence of type 2 diabetes mellitus and essential hypertension on the angiographic characteristics of coronary heart disease in coronary heart disease patients

作　　者：宫建丽[1] 李文华[1] 孔香云[1] 张秀洲[1] 张祖煌[1] 唐元升[1] 朱兴雷[1] 

机构地区：[1]山东省立医院心内科,济南250021

出　　处：《军医进修学院学报》2006年第6期458-460,共3页Academic Journal of Pla Postgraduate Medical School

基　　金：2003-山东省科技发展计划35号

摘　　要：目的:探讨冠心病(CHD)患者合并2型糖尿病及高血压病对冠状动脉病变特点的影响。方法:研究对象按是否合并2型糖尿病及高血压病进行分组,对其冠状动脉造影特点进行对比分析。结果:与单纯冠心病组相比,冠心病合并高血压组冠状动脉受累程度高,血管狭窄程度重,弥漫性血管病变多见,冠心病合并2型糖尿病组冠状动脉受累程度高,弥漫性血管病变多见;与冠心病合并高血压组相比,冠心病合并2型糖尿病组冠状动脉受累程度高,血管狭窄程度重,弥漫性血管病变多见;与冠心病合并2型糖尿病合并高血压组相比,冠心病合并高血压组冠状动脉总受累程度轻,弥漫性血管病变少见,而冠心病合并2型糖尿病组与之在冠状动脉受累程度、狭窄部位、狭窄程度及弥漫性血管病变所占比例的差异均无统计学意义。结论:冠心病患者合并2型糖尿病及高血压均能加重冠状动脉的病变程度,且以冠心病患者合并2型糖尿病的冠状动脉病变更严重。Objective：To study the influence of type 2 diabetes mellitus and essential hypertension on the angiographic characteristics of coronary heart disease （CHD） in CHD patients. Methods： The study was carried by the analysis of the data from selective coronary angiography in CHD patients in different groups divided by with or without type 2 diabetes mellitus（DM） and essential hypertension （EH）. Results： Compared with simple CHD patients, CHD patients with EH had greater rate of coronary vessels involvement, narrow degree more severe and more diffuse lesions, while CHD patients with DM tended to have greater rate of coronary vessels involvement and more diffuse lesions. Compared with CHD patients with EH, CHD patients with DM had greater rate of coronary vessels involvement, narrow degree more severe and more diffuse lesions. Compared with CHD patients with DM and EH, CHD patients with EH had lower rate of coronary vessels involvement and less diffuse lesions, while CHD patients with DM had no significant difference in coronary vessel involvements, narrow degree of vascular lesions, narrow positions and diffuse lesions. Conclusion： Both essential hypertension and type 2 diabetes mellitus especially type 2 diabetes mellitns could aggravate the angio-lesions in CHD patients.

关 键 词：冠状动脉疾病 糖尿病 2型 高血压 冠状血管造影术 

分 类 号：R541.4[医药卫生—心血管疾病]