5岁以下健康儿童流感嗜血杆菌携带状态的研究  

RESEARCH OF HEAMOPHILUS INFLUENZA'S POPULATION CARRIAGE IN CHILDREN UNDER THE AGE OF 5 YEARS OLD

作　　者：李瑞池[1] 刘树贤[2] 刘殿武[2] 王俊荣[3] 

机构地区：[1]河北医科大学第一医院,石家庄050031 [2]河北医科大学公共卫生学院 [3]河北省儿童医院

出　　处：《现代预防医学》2007年第1期135-137,共3页Modern Preventive Medicine

摘　　要：[目的]流感嗜血杆菌(Hi)是引起儿童细菌性感染的主要病原菌,国内对Hi携带的研究资料较少,本文对石家庄市5岁以下健康儿童Hi感染的流行病学分布情况进行了研究,为制订防治对策提供参考依据。[方法]在石家庄市区整群随机抽样,调查1045例5岁以下健康儿童,取鼻咽拭子标本,用改良巧克力培养基,常规Hi培养并鉴定菌型。[结果](1)Hi携带率为15.6%,生物型Ⅰ、Ⅱ、Ⅲ型共98例(70.5%)为优势菌型。(2)经Logistic多元回归分析显示Hi携带与年龄、出生时身高、家庭人均经济收入和裂纹舌有关。[结论]石家庄市5岁以下正常儿童Hi携带率为15.6%,6个月至2岁儿童Hi携带率最高(22.4%)。Hi携带可能受遗传等综合因素影响。把中医舌诊试用于Hi携带的观察研究,显示了裂纹舌与Hi感染有关,为中西医结合提供参考依据。[Objective] Haemophilus influenza is a major pathogenic bacterinm of bacterial invasive infections in children. The study was intended to provide essential information to research the Epidemiology of Hi infection and look for the methods of prevention and controlling of Hi infection. [Methods] 1045 eases of normal children less than 5 years of age living in shijiazhuang city were investigated with cluster sampling, The nasophargngeal specimens were cultured on the improved Chocolate media and indentified bacterial type routinely. [Results] （1） The carriage rate of Hi was 15.6%. The Biotype Ⅰ .Ⅱ and Ⅲ were the domination of Hi. and accounted for 98 cases （70.5%） . （2） The major factors of affecting carriage were age, height of birth, and mean incomes of family. [Conclusions] The Hi carriage rate in children less than 5 yeas of age residing Shijiazhuang City is 15.6%. The carriage peaks in children 6-24 months of age （22.4%） . The carriage rate is responding for general faetors, such as heredity. Surveying the Hi carriage using Lingual Diagnosis methods of Chinese Medicine shows the significant correlation between Hi fection and fissured tongue, provides basis for combination of traditinal and western medicine.

关 键 词：流感嗜血杆菌 儿童 人群携带率 

分 类 号：R181.22[医药卫生—流行病学]